The identification and characterization of human Sister-of-Mammalian Grainyhead (SOM) expands the grainyhead-like family of developmental transcription factors

SB Ting, T Wilanowski, L Cerruti, LL Zhao… - Biochemical …, 2003 - portlandpress.com
The Drosophila gene grainyhead is the founding member of a large family of genes
encoding developmental transcription factors that are highly conserved from fly to human …

Repression of human immunodeficiency virus type 1 through the novel cooperation of human factors YY1 and LSF

F Romerio, MN Gabriel, DM Margolis - Journal of virology, 1997 - Am Soc Microbiol
A subpopulation of stably infected CD4+ cells capable of producing virus upon stimulation
has been identified in human immunodeficiency virus (HIV)-positive individuals (T.-W. Chun …

Essential role of the ERK/MAPK pathway in blood-placental barrier formation

V Nadeau, J Charron - Development, 2014 - journals.biologists.com
The mammalian genome contains two ERK/MAP kinase kinase genes, Map2k1 and
Map2k2, which encode dual-specificity kinases responsible for ERK activation. Loss of …

Efficient and specific targeting of Polycomb group proteins requires cooperative interaction between Grainyhead and Pleiohomeotic

A Blastyák, RK Mishra, F Karch… - Molecular and cellular …, 2006 - Taylor & Francis
Specific targeting of the protein complexes formed by the Polycomb group of proteins is
critically required to maintain the inactive state of a group of developmentally regulated …

[HTML][HTML] Inhibition of the mammalian transcription factor LSF induces S‐phase‐dependent apoptosis by downregulating thymidylate synthase expression

CMH Powell, TL Rudge, Q Zhu, LF Johnson… - The EMBO …, 2000 - embopress.org
The thymidylate synthase (TS) gene, which is induced at the G 1–S transition in growth‐
stimulated cells, encodes an enzyme that is essential for DNA replication and cell survival …

Grainy head and its target genes in epithelial morphogenesis and wound healing

S Wang, C Samakovlis - Current topics in developmental biology, 2012 - Elsevier
Abstract The Grainy head (Grh) family of transcription factors is characterized by a unique
DNA-binding domain that binds to a conserved consensus sequence. Nematodes and flies …

Lineage-specific and ubiquitous biological roles of the mammalian transcription factor LSF

J Veljkovic, U Hansen - Gene, 2004 - Elsevier
Transcriptional regulation in mammalian cells is driven by a complex interplay of multiple
transcription factors that respond to signals from either external or internal stimuli. A single …

Map2k1 and Map2k2 genes contribute to the normal development of syncytiotrophoblasts during placentation

V Nadeau, S Guillemette, LF Bélanger, O Jacob, S Roy… - 2009 - journals.biologists.com
The mammalian genome contains two ERK/MAP kinase kinase genes, Map2k1 and
Map2k2, which encode dual-specificity kinases responsible for ERK/MAP kinase activation …

The fold recognition of CP2 transcription factors gives new insights into the function and evolution of tumor suppressor protein p53

K Kokoszyńska, J Ostrowski, L Rychlewski… - Cell Cycle, 2008 - Taylor & Francis
The CP2 transcription factor (TFCP2) is a critical regulator of erythroid gene expression.
Apart from the involvement in the transcriptional switch of globin gene promoters it activates …

The transcriptional factor LBP-1c/CP2/LSF gene on chromosome 12 is a genetic determinant of Alzheimer's disease

JC Lambert, L Goumidi, FWD Vrièze… - Human Molecular …, 2000 - academic.oup.com
Although the ε4 allele of the apolipoprotein E gene appears as an important biological
marker for Alzheimer's disease (AD) susceptibility, other genetic determinants are clearly …