Cryptosporidium emerged as a leading global cause of severe diarrheal disease in children.
The parasite occupies a unique intracellular niche at the brush border of intestinal epithelial …

Cryptosporidiosis is a water-and food-borne zoonotic disease caused by the protozoon
parasite of the genus Cryptosporidium. C. hominis and C. parvum are the main two species …

Cryptosporidium is a leading cause of diarrheal disease in children and an important
contributor to early childhood mortality. The parasite invades and extensively remodels …

Cryptosporidium parasites replicate within intestinal epithelial cells and are an important
cause of diarrhoeal disease in young children and in patients with primary and acquired …

Parasites and their hosts are engaged in reciprocal coevolution that balances competing
mechanisms of virulence, resistance, and evasion. This often leads to host specificity, but …

Cryptosporidium can cause severe diarrhea and morbidity, but many infections are
asymptomatic. Here, we studied the immune response to a commensal strain of …

Cryptosporidium infects gastrointestinal epithelium and is a leading cause of infectious
diarrhea and diarrheal-related death in children worldwide. There are no vaccines and no …

Apicomplexan parasites comprise significant pathogens of humans, livestock and wildlife,
but also represent a diverse group of eukaryotes with interesting and unique cell biology …

Cryptosporidium parvum is an obligate intracellular parasite with a highly reduced
mitochondrion that lacks the tricarboxylic acid cycle and the ability to generate ATP, making …

The malaria parasite life cycle alternates between two hosts: a vertebrate and the female
Anopheles mosquito vector. Cell division, proliferation, and invasion are essential for …