Equol is the most potent soy isoflavone metabolite and is produced by specific intestinal
microorganisms of mammals. It has promising application possibilities for preventing chronic …

Cofactors are crucial chemicals that maintain cellular redox balance and drive the cell to do
synthetic and catabolic reactions. They are involved in practically all enzymatic activities that …

(S)-Equol is one of the most bioactive metabolites of the isoflavones with immense
nutritional and pharmaceutical value. Soy whey is the major liquid byproduct of the soy …

The active metabolite (S)-equol, derived from daidzein by gut microbiota, exhibits superior
antioxidative activity compared with its precursor and plays a vital role in human health. As …

With its estrogenic activity,(S)-equol plays an important role in maintaining host health and
preventing estrogen-related diseases. Exclusive production occurs through the …

Deoxycholic acid (DCA) has been authorized by the Federal Drug Agency for cosmetic
reduction of redundant submental fat. The hydroxylated product (6β-OH DCA) was …

Daidzein is an abundant polyphenol present in soy and other legumes. It accumulates
mostly in seed and seed pod during the plant development in response to biotic and abiotic …

Charles University Faculty of Pharmacy in Hradec Kralove Department of Pharmacology &
Toxicology Candidate: Thomas Migkos, M. Sc. Supervisor: Prof. Přemysl Mladěnka, Pharm …