Colorectal cancer (CRC) stands as one of the most prevalent form of cancer globally,
causing a significant number of deaths, surpassing 0.9 million in the year 2020. According to …

This study demonstrates that low doses (somewhat above the No Observed Adverse Effect
Level, NOAEL) of the mycoestrogen zearalenone (ZEN) and its metabolites display …

It has been reported that estrogen receptors (ERs) participate in carcinogenesis by directly
regulating NOD-like receptors (NLRs). However, the expression profiles of ERs and NLRs in …

Background Although estrogen (ERα/ERβ), progesterone (PGR), and androgen (AR)
receptors are pathologically altered in colorectal cancer (CRC), their simultaneous …

This study aimed to evaluate the expression of H2B monoubiquitination enzyme (uH2B) and
ubiquitin-specific protease enzyme 22 (USP22) in colon carcinoma and establish a …

Zearalenone and its metabolites, α-zearalenol and β-zearalenol, demonstrate estradiol-like
activity and disrupt physiological functions in animals. This article evaluates the carryover of …

This study was conducted to determine if a low monotonic dose of zearalenone (ZEN) affects
the immunohistochemical expression (IE) of oestrogen receptor alpha (ERα) and oestrogen …

We reported that high estrogen receptor beta (ERβ) expression is independently associated
with better prognosis in female colorectal cancer (CRC) patients. However, estrogen …

In normal colon tissue, oestrogen receptor alpha (ERα) is expressed at low levels, while
oestrogen receptor beta (ERβ) is considered the dominant subtype. However, in colon …

Simple Summary Selective estrogen receptor modulators are a major treatment modality for
estrogen receptor-positive breast cancers, but the emergence of resistance or a lack of initial …