Anti-caspase-3 preconditioning increases proinsulin secretion and deteriorates posttransplant function of isolated human islets

D Brandhorst, H Brandhorst, V Maataoui, A Maataoui… - Apoptosis, 2013 - Springer
Human islet isolation is associated with adverse conditions inducing apoptosis and
necrosis. The aim of the present study was to assess whether antiapoptotic preconditioning …

Islet cell transplantation

JA Emamaullee, A Pepper, AMJ Shapiro - Principles of regenerative …, 2019 - Elsevier
Abstract The Edmonton Protocol for clinical islet transplantation offers hope for patients with
diabetes that a life without insulin injections is possible. More than 1000 patients with type 1 …

Impact of Anti–Insulin Antibodies on Islet Transplantation Outcome: Data From the GRAGIL Network

S Lablanche, S Borot, O Thaunat, F Bayle… - …, 2014 - journals.lww.com
Background In patients with type 1 diabetes, insulin antibodies (IA), altering the
pharmacokinetics of circulating insulin, might be associated with high glucose concentration …

Failure mode and effect analysis in human islet isolation: from the theoretical to the practical risk

Q Perrier, V Lavallard, N Pernin, CH Wassmer… - Islets, 2021 - Taylor & Francis
This study aimed to assess the global mapping risk of human islet isolation, using a failure
mode and effect analysis (FMEA), and highlight the impact of quality assurance procedures …

[HTML][HTML] Transplante de pâncreas e ilhotas em portadores de diabetes melito

JR Sá, AM Gonzalez, CS Melaragno… - … de Endocrinologia & …, 2008 - SciELO Brasil
O transplante simultâneo de pâncreas/rim tem indicações específicas, riscos e benefícios. O
procedimento, cada vez mais realizado, traz vantagens se comparado ao paciente em …

International workshop: islet transplantation without borders enabling islet transplantation in G reece with international collaboration and innovative technology

KK Papas, T Karatzas, T Berney, T Minor… - Clinical …, 2013 - Wiley Online Library
Recently, initiatives have been undertaken to establish an islet transplantation program in A
thens, G reece. A major hurdle is the high cost associated with the establishment and …

Presente y futuro del trasplante de islotes pancreáticos, un tratamiento innovador para la diabetes tipo 1

A Sabogal, LA Casas, LG Arango… - Revista …, 2015 - revistaendocrino.org
Introducción el trasplante de islotes pancreáticos (TI*) se ha convertido en una opción
terapéutica prometedora para algunos pacientes diabéticos con historia de hipoglicemia …

Lessons Learned from Clinical Trials of Islet Transplantation

T Berney, L Badet, E Berishvili, F Buron… - Pluripotent Stem Cell …, 2024 - Springer
Islet of Langerhans transplantation has gained a clear place in the therapeutic
armamentarium for type 1 diabetes and is now considered standard-of-care in many …

Pancreas and islet transplantation in patients with diabetes mellitus

JR Sá, AM Gonzalez, CS Melaragno… - … de Endocrinologia & …, 2008 - SciELO Brasil
O transplante simultâneo de pâncreas/rim tem indicações específicas, riscos e benefícios. O
procedimento, cada vez mais realizado, traz vantagens se comparado ao paciente em …

[HTML][HTML] Transplante de ilhotas na prática clínica: estado atual e perspectivas

FG Eliaschewitz, DR Franco, TR Mares-Guia… - … de Endocrinologia & …, 2009 - SciELO Brasil
O transplante de ilhotas é um procedimento em desenvolvimento, como alternativa para o
tratamento do diabetes tipo 1 que está na fronteira entre o experimental e o clínico. É uma …