Rutin as a potent antioxidant: Implications for neurodegenerative disorders

AB Enogieru, W Haylett, DC Hiss… - Oxidative medicine …, 2018 - Wiley Online Library
A wide range of neurodegenerative diseases (NDs), including Alzheimer's disease,
Parkinson's disease, Huntington's disease, and prion diseases, share common mechanisms …

Amyloid cascade hypothesis: Pathogenesis and therapeutic strategies in Alzheimer's disease

SH Barage, KD Sonawane - Neuropeptides, 2015 - Elsevier
Alzheimer's disease is an irreversible, progressive neurodegenerative disorder. Various
therapeutic approaches are being used to improve the cholinergic neurotransmission, but …

[HTML][HTML] Theranostic F-SLOH mitigates Alzheimer's disease pathology involving TFEB and ameliorates cognitive functions in Alzheimer's disease models

A Iyaswamy, X Wang, S Krishnamoorthi… - Redox biology, 2022 - Elsevier
Accumulation of amyloid-β (Aβ) oligomers and phosphorylated Tau aggregates are crucial
pathological events or factors that cause progressive neuronal loss, and cognitive …

Therapeutic potential of culinary-medicinal mushrooms for the management of neurodegenerative diseases: diversity, metabolite, and mechanism

CW Phan, P David, M Naidu, KH Wong… - Critical reviews in …, 2015 - Taylor & Francis
Mushrooms have long been used not only as food but also for the treatment of various
ailments. Although at its infancy, accumulated evidence suggested that culinary-medicinal …

Therapeutic strategies targeting amyloid-β in Alzheimer's disease

L Pinheiro, C Faustino - Current Alzheimer Research, 2019 - ingentaconnect.com
Alzheimer's disease (AD) is a neurodegenerative disorder linked to protein misfolding and
aggregation. AD is pathologically characterized by senile plaques formed by extracellular …

Neuroprotective effect of berberine against environmental heavy metals-induced neurotoxicity and Alzheimer's-like disease in rats

HM Hussien, A Abd-Elmegied, DA Ghareeb… - Food and chemical …, 2018 - Elsevier
Heavy metals are reported as neurodegenerative disorders progenitor. They play a role in
the precipitation of abnormal β-amyloid protein and hyper-phosphorylated tau, the main …

Protein aggregation and neurodegenerative diseases: From theory to therapy

V Kumar, N Sami, T Kashav, A Islam, F Ahmad… - European journal of …, 2016 - Elsevier
The study of protein misfolding and aggregation saw resurgence in the last decade.
Aggregation is the main cause of several human neurodegenerative diseases which makes …

Nec‐1 alleviates cognitive impairment with reduction of Aβ and tau abnormalities in APP/PS 1 mice

SH Yang, DK Lee, J Shin, S Lee, S Baek… - EMBO molecular …, 2017 - embopress.org
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by cognitive
symptoms of learning and memory deficits. Such cognitive impairments are attributed to …

Mathematical model on Alzheimer's disease

W Hao, A Friedman - BMC systems biology, 2016 - Springer
Background Alzheimer disease (AD) is a progressive neurodegenerative disease that
destroys memory and cognitive skills. AD is characterized by the presence of two types of …

[HTML][HTML] Essential oils as treatment strategy for Alzheimerʼs disease: Current and future perspectives

A Benny, J Thomas - Planta medica, 2019 - thieme-connect.com
Alzheimerʼs disease is a multifarious neurodegenerative disease that causes cognitive
impairment and gradual memory loss. Several hypotheses have been put forward to …