Global Challenge of Multidrug-Resistant Acinetobacter baumannii

F Perez, AM Hujer, KM Hujer, BK Decker… - Antimicrobial agents …, 2007 - Am Soc Microbiol
We may soon be facing the end of the “antibiotic era.” The initial and seemingly unstoppable
success of antibiotics, the fruit of human ingenuity, has been countered by an escalation of …

[HTML][HTML] Resistance integrons and super-integrons

AC Fluit, FJ Schmitz - Clinical microbiology and infection, 2004 - Elsevier
Integrons are genetic elements composed of a gene encoding an integrase, gene cassettes
and an integration site for the gene cassettes (att). The integrase excises and integrates the …

Prevalence of VIM- and GIM-producing Acinetobacter baumannii from patients with severe urinary tract infection

SAS Girija, VP Jayaseelan… - Acta microbiologica et …, 2018 - akjournals.com
Carbapenems are administered as the final drug of choice for treating complicated
nosocomial infections caused by multidrug-resistant Acinetobacter baumannii strains. It is …

[HTML][HTML] Antimicrobial resistance of Acinetobacter spp. in Europe

M Van Looveren, H Goossens… - Clinical microbiology …, 2004 - Elsevier
Bacteria of the genus Acinetobacter are ubiquitous in nature. These organisms were
invariably susceptible to many antibiotics in the 1970s. Since that time, acinetobacters have …

Diversity of aminoglycoside-resistance genes and their association with class 1 integrons among strains of pan-European Acinetobacter baumannii clones

A Nemec, L Dolzani, S Brisse… - Journal of medical …, 2004 - microbiologyresearch.org
The purpose of the present study was to investigate the diversity of the genes encoding
aminoglycoside-modifying enzymes and their association with class 1 integrons in three pan …

Identification of Epidemic Strains ofAcinetobacter baumannii by Integrase Gene PCR

JGM Koeleman, J Stoof, MW Van Der Bijl… - Journal of clinical …, 2001 - Am Soc Microbiol
Forty-eight clinical Acinetobacter isolates with different epidemic behavior were investigated
for the presence of integrons and plasmids and for antibiotic susceptibility. Integrons were …

Identification of a new geographically widespread multiresistant Acinetobacter baumannii clone from European hospitals

H Van Dessel, L Dijkshoorn, T van der Reijden… - Research in …, 2004 - Elsevier
The aim of the study was to investigate the genetic diversity of Acinetobacter baumannii
clinical strains that had previously been allocated to three major groups based on …

Molecular Characterization of Integrons inAcinetobacter baumannii: Description of a Hybrid Class 2 Integron

MC Ploy, F Denis, P Courvalin… - Antimicrobial agents and …, 2000 - Am Soc Microbiol
Twenty Acinetobacter baumannii strains resistant to various antibiotics were analyzed for
integron content and sequences of the amplification products. Sixteen clinical isolates had a …

Prevalence of carbapenem-hydrolyzing OXA-type β-lactamases among Acinetobacter baumannii in patients with severe urinary tract infection

SA Girija, JV Priyadharsini… - Acta Microbiologica et …, 2020 - akjournals.com
Acinetobacter baumannii produces carbapenemase-hydrolyzing class D β-lactamases
(CHDLs) as one of the major drug resistance mechanisms. This investigation is thus aimed …

Class 1 integron in staphylococci

Z Xu, L Li, L Shi, ME Shirtliff - Molecular biology reports, 2011 - Springer
As a major concern in public health, methicillin-resistant staphylococci (MRS) still remains
one of the most prevalent pathogens that cause nosocomial infections throughout the world …