Breast cancer is a complex disease encompassing multiple tumor entities, each
characterized by distinct morphology, behavior and clinical implications. Besides estrogen …

Breast cancer is a common malignancy among women worldwide. Regardless of the
economic status of a country, breast cancer poses a burden in prevention, diagnosis and …

How tumor cells genetically lose antigenicity and evade immune checkpoints remains
largely elusive. We report that tissue-specific expression of the human long noncoding RNA …

Ferroptosis is a specialized iron-dependent cell death that is associated with lethal lipid
peroxidation. Modulation of ferroptosis may have therapeutic potential since it has been …

In this study we investigated the anti-cancer effect of Moringa oleifera leaves, bark and seed
extracts. When tested against MDA-MB-231 and HCT-8 cancer cell lines, the extracts of …

p53 is a nuclear transcription factor with a pro-apoptotic function. Since over 50% of human
cancers carry loss of function mutations in p53 gene, p53 has been considered to be one of …

The majority of estrogen receptor (ER)-positive breast cancers are treated with endocrine
therapy. While this is effective, acquired resistance to therapies targeted against ER is a …

Cancer cells are characterized by genetic and epigenetic alterations and phytochemicals,
epigenetic modulators, are considered as promising candidates for epigenetic therapy of …

Protein/peptide drugs possess unique advantages, such as high pharmacological potency,
molecular specificity, multifunctionality, and low toxicity, and thus hold great potential for use …

During different stages of tumor development the immune system can either identify and
destroy tumors, or promote their growth. Therapies targeting the immune system have …