An Overview of Cannabidiol as a Multifunctional Drug: Pharmacokinetics and Cellular Effects

N Martinez Naya, J Kelly, G Corna, M Golino… - Molecules, 2024 - mdpi.com
Cannabidiol (CBD), a non-psychoactive compound derived from Cannabis Sativa, has
garnered increasing attention for its diverse therapeutic potential. This comprehensive …

Cannabidiol alleviates perfluorooctanesulfonic acid-induced cardiomyocyte apoptosis by maintaining mitochondrial dynamic balance and energy metabolic …

X Wang, T Xu, D Luo, S Li, X Tang, J Ding… - Journal of agricultural …, 2023 - ACS Publications
Perfluorooctanesulfonic acid (PFOS), a fluorine-containing organic compound, can be
widely detected in the environment and living organisms. Accumulating evidence has shown …

Drugs of abuse and heart failure

AF Grubb, SJ Greene, M Fudim, T Dewald… - Journal of Cardiac …, 2021 - Elsevier
Substance use is common among those with heart failure (HF) and is associated with worse
clinical outcomes. Alcohol, tobacco, cannabis, and cocaine are commonly abused …

[HTML][HTML] Development and pharmacokinetic evaluation of a self-nanoemulsifying drug delivery system for the oral delivery of cannabidiol

LY Kok, P Bannigan, F Sanaee, JC Evans… - European Journal of …, 2022 - Elsevier
The number of lipophilic drug candidates in pharmaceutical discovery pipelines has
increased in recent years. These drugs often possess physicochemical properties that result …

Ndufs1 deficiency aggravates the mitochondrial membrane potential dysfunction in pressure overload‐induced myocardial hypertrophy

R Zou, J Tao, J Qiu, W Shi, M Zou… - Oxidative Medicine …, 2021 - Wiley Online Library
Mitochondrial dysfunction has been suggested to be the key factor in the development and
progression of cardiac hypertrophy. The onset of mitochondrial dysfunction and the …

Benefits, toxicity and current market of cannabidiol in edibles

G Astray, JC Mejuto, J Xiao… - Critical Reviews in Food …, 2023 - Taylor & Francis
The commercialization of products with cannabidiol (CBD) has undergone a significant
increase. These products can be presented in different forms such as baked goods …

How do phytocannabinoids affect cardiovascular health? An update on the most common cardiovascular diseases

S Dziemitko, E Harasim-Symbor… - … Advances in Chronic …, 2023 - journals.sagepub.com
Cardiovascular disease (CVD) causes millions of deaths worldwide each year. Despite the
great progress in therapies available for patients with CVD, some limitations, including drug …

The putative cannabinoid-secreting trichome of Trema micrantha (L.) Blume (Cannabaceae)

SP Teixeira, IC Nascimento, MP Grejo, VG Leite… - Protoplasma, 2024 - Springer
Trema, a genus of the popularly known Cannabaceae, has recently been the subject of
cannabinoid bioprospection. T. micrantha is a tree with pharmacological potential widely …

A narrative review of the ethnomedicinal usage of Cannabis sativa Linnaeus as traditional phytomedicine by folk medicine practitioners of Bangladesh

SSM Shakil, M Gowan, K Hughes, MNK Azam… - Journal of Cannabis …, 2021 - Springer
Background There is a worldwide interest in the use of Cannabis sativa for biomedicine
purposes. Cannabis has ethnomedicinal usage as a natural medicine in Bangladesh and …

Therapeutic effect of cannabidiol on myocardial arachidonic acid content in various lipid fractions in a rat model of obesity

K Sztolsztener, W Bzdęga… - Prostaglandins & Other …, 2023 - Elsevier
The study explored the potential protective influence of cannabidiol (CBD) on myocardial
inflammation state, with a special focus on arachidonic acid (AA), and oxidative balance in …