Diabetic retinopathy (DR) is an increasingly frequent cause of blindness across populations;
however, the events that initiate pathophysiology of DR remain elusive. Strong preclinical …

Vasoregression is a common phenomenon underlying physiological vessel development as
well as pathological microvascular diseases leading to peripheral neuropathy, nephropathy …

Polycystic ovary syndrome (PCOS) is frequently associated with non-alcoholic fatty liver
disease (NAFLD), but the mechanisms involved in the development of NAFLD in PCOS are …

A Mediterranean diet appears to have health benefits in many domains of human health,
mediated perhaps by its anti-inflammatory effects. Metabolism of fatty acids and subsequent …

We have investigated the long term effects of insulin dependent diabetes mellitus (IDDM) on
the fatty acid profile of tissues in aging rats. For this purpose, a rat model for IDDM was …

Introduction Circadian rhythm is a natural endogenous process occurring roughly every 24
hours. Circadian rhythm dysfunction is involved in diabetic retinopathy (DR) pathogenesis …

Mutations in BSCL2 underlie human congenital generalized lipodystrophy type 2 disease.
We previously reported that Bscl2−/− mice develop lipodystrophy of white adipose tissue …

Inflammation is a powerful immune countermeasure to tissue damage and infection. The
inflammatory response is complex and requires the involvement of myriad signaling …

Background: The competing endogenous RNA (ceRNA) network plays an important role in
the occurrence and development of a variety of diseases. This study aimed to construct a …

Purpose: Low levels of the long chain polyunsaturated fatty acid (LCPUFA)
docosahexaenoic acid (DHA) have been implicated in retinopathy of prematurity (ROP) …