Exosome-derived microRNAs of human milk and their effects on infant health and development
BC Melnik, W Stremmel, R Weiskirchen, SM John… - Biomolecules, 2021 - mdpi.com
Multiple biologically active components of human milk support infant growth, health and
development. Milk provides a wide spectrum of mammary epithelial cell-derived …
development. Milk provides a wide spectrum of mammary epithelial cell-derived …
Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis
Y Tang, LJ Yang, H Liu, YJ Song, QQ Yang, Y Liu… - Cell reports, 2023 - cell.com
Obesity, particularly increased visceral fat, positively correlates with various metabolic
challenges, including atherosclerosis, but the mechanism is not fully understood. The aim of …
challenges, including atherosclerosis, but the mechanism is not fully understood. The aim of …
Exosomal microRNAs in milk from mothers delivering preterm infants survive in vitro digestion and are taken up by human intestinal cells
Scope This study investigates the ability of preterm milk exosomes to survive
gastric/pancreatic digestion, internalization by intestinal epithelia, and the microRNAs …
gastric/pancreatic digestion, internalization by intestinal epithelia, and the microRNAs …
LncRNA H19 ameliorates myocardial infarction‐induced myocardial injury and maladaptive cardiac remodelling by regulating KDM3A
B Zhang, H Jiang, J Chen, Q Hu… - Journal of cellular …, 2020 - Wiley Online Library
Myocardial infarction (MI) remains the leading cause of morbidity and mortality worldwide,
and novel therapeutic targets still need to be investigated to alleviate myocardial injury and …
and novel therapeutic targets still need to be investigated to alleviate myocardial injury and …
[HTML][HTML] Non-coding RNAs as biomarkers of myocardial infarction
Non-coding RNAs (ncRNAs) encompass a family of ubiquitous RNA molecules that lack
protein-coding potential and have tissue-specific expression. A significant body of evidence …
protein-coding potential and have tissue-specific expression. A significant body of evidence …
Function and therapeutic potential of noncoding RNAs in cardiac fibrosis
EE Creemers, E Van Rooij - Circulation research, 2016 - Am Heart Assoc
Cardiac fibrosis as a result of excessive extracellular matrix deposition leads to stiffening of
the heart, which can eventually lead to heart failure. An important event in cardiac fibrosis is …
the heart, which can eventually lead to heart failure. An important event in cardiac fibrosis is …
Mechanisms underlying the influence of oestrogen on cardiovascular physiology in women
S Novella, D Pérez‐Cremades… - The Journal of …, 2019 - Wiley Online Library
Women show a lower incidence of cardiovascular diseases than age‐matched men, but this
benefit disappears after menopause. Oestrogen‐mediated vascular actions are mainly …
benefit disappears after menopause. Oestrogen‐mediated vascular actions are mainly …
Upregulation of microRNA-22 contributes to myocardial ischemia-reperfusion injury by interfering with the mitochondrial function
JK Du, BH Cong, Q Yu, H Wang, L Wang… - Free Radical Biology …, 2016 - Elsevier
Mitochondrial oxidative damage is critically involved in cardiac ischemia reperfusion (I/R)
injury. MicroRNA-22 (miR-22) has been predicted to potentially target sirtuin-1 (Sirt1) and …
injury. MicroRNA-22 (miR-22) has been predicted to potentially target sirtuin-1 (Sirt1) and …
Clinical significance of MicroRNAs, long non-coding RNAs, and CircRNAs in cardiovascular diseases
Based on recent research, the non-coding genome is essential for controlling genes and
genetic programming during development, as well as for health and cardiovascular …
genetic programming during development, as well as for health and cardiovascular …