Functional annotation of a divergent genome using sequence and structure-based similarity
D Svedberg, RR Winiger, A Berg, H Sharma… - BMC genomics, 2024 - Springer
Background Microsporidia are a large taxon of intracellular pathogens characterized by
extraordinarily streamlined genomes with unusually high sequence divergence and many …
extraordinarily streamlined genomes with unusually high sequence divergence and many …
High-throughput small molecule screen identifies inhibitors of microsporidia invasion and proliferation in C. elegans
BM Murareanu, NV Antao, W Zhao, A Dubuffet… - Nature …, 2022 - nature.com
Microsporidia are a diverse group of fungal-related obligate intracellular parasites that infect
most animal phyla. Despite the emerging threat that microsporidia represent to humans and …
most animal phyla. Despite the emerging threat that microsporidia represent to humans and …
Ultrastructural insights into the microsporidian infection apparatus reveal the kinetics and morphological transitions of polar tube and cargo during host cell invasion
H Sharma, N Jespersen, K Ehrenbolger… - PLoS …, 2024 - journals.plos.org
During host cell invasion, microsporidian spores translocate their entire cytoplasmic content
through a thin, hollow superstructure known as the polar tube. To achieve this, the polar tube …
through a thin, hollow superstructure known as the polar tube. To achieve this, the polar tube …
Transcriptomic changes in the microsporidia proliferation and host responses in congenitally infected embryos and larvae
Z Shen, Z Ke, Q Yang, ST Ghebremichael, T Li, T Li… - BMC genomics, 2024 - Springer
Congenital infection caused by vertical transmission of microsporidia N. bombycis can result
in severe economic losses in the silkworm-rearing industry. Whole-transcriptome analyses …
in severe economic losses in the silkworm-rearing industry. Whole-transcriptome analyses …
Characterization of the Largest Secretory Protein Family, Ricin B Lectin-like Protein, in Nosema bombycis: Insights into Microsporidian Adaptation to Host
J Xu, J Luo, J Chen, CR Vossbrinck, T Li, Z Zhou - Journal of Fungi, 2022 - mdpi.com
Microsporidia are a group of obligate intracellular pathogens infecting nearly all animal
phyla. The microsporidian Nosema bombycis has been isolated from several lepidopteran …
phyla. The microsporidian Nosema bombycis has been isolated from several lepidopteran …
Functional annotation of a divergent genome using sequence and structure-based homology.
D Svedberg, RR Winiger, A Berg, H Sharma… - bioRxiv, 2023 - biorxiv.org
Background Microsporidia are a large taxon of intracellular pathogens characterized by
extraordinarily streamlined genomes with unusually high sequence divergence and many …
extraordinarily streamlined genomes with unusually high sequence divergence and many …
Ribosome clustering and surface layer reorganization in the microsporidian host-invasion apparatus
H Sharma, N Jespersen, K Ehrenbolger, LA Carlson… - bioRxiv, 2023 - biorxiv.org
During host cell invasion, microsporidian spores translocate their entire cytoplasmic content
through a thin, hollow superstructure known as the polar tube. To achieve this, the polar tube …
through a thin, hollow superstructure known as the polar tube. To achieve this, the polar tube …