Endometriosis: epidemiology, classification, pathogenesis, treatment and genetics (review of literature)

B Smolarz, K Szyłło, H Romanowicz - International journal of molecular …, 2021 - mdpi.com
Endometriosis is a “mysterious” disease and its exact cause has not yet been established.
Among the etiological factors, congenital, environmental, epigenetic, autoimmune and …

The main theories on the pathogenesis of endometriosis

J Lamceva, R Uljanovs, I Strumfa - International journal of molecular …, 2023 - mdpi.com
Endometriosis is a complex disease, which is defined by abnormal growth of endometrial
tissue outside the uterus. It affects about 10% of women of reproductive age all over the …

[HTML][HTML] CCL5/CCR5 axis in human diseases and related treatments

Z Zeng, T Lan, Y Wei, X Wei - Genes & diseases, 2022 - Elsevier
To defense harmful stimuli or maintain the immune homeostasis, the body produces and
recruits a superfamily of cytokines such as interleukins, interferons, chemokines etc. Among …

The role of gut and genital microbiota and the estrobolome in endometriosis, infertility and chronic pelvic pain

ME Salliss, LV Farland, ND Mahnert… - Human reproduction …, 2022 - academic.oup.com
BACKGROUND Endometriosis is a chronic, burdensome condition that is historically
understudied. Consequently, there is a lack of understanding of the etiology of the disease …

Pharmaceuticals targeting signaling pathways of endometriosis as potential new medical treatment: A review

SW Hung, R Zhang, Z Tan, JPW Chung… - Medicinal research …, 2021 - Wiley Online Library
Endometriosis (EM) is defined as endometrial tissues found outside the uterus. Growth and
development of endometriotic cells in ectopic sites can be promoted via multiple pathways …

Biomarkers for the noninvasive diagnosis of endometriosis: state of the art and future perspectives

CV Anastasiu, MA Moga, A Elena Neculau… - International journal of …, 2020 - mdpi.com
Background: Early and accurate diagnosis of endometriosis is crucial for the management of
this benign, yet debilitating pathology. Despite the advances of modern medicine, there is no …

[HTML][HTML] Dietary supplements for treatment of endometriosis: A review

PY Bahat, I Ayhan, EU Ozdemir… - Acta Bio Medica: Atenei …, 2022 - ncbi.nlm.nih.gov
As search for optimal therapy continues for endometriosis, aid of dietary supplements is
gaining attention. Supplements can be used for their anti-inflammatory, anti-oxidant, anti …

Plants as source of new therapies for endometriosis: a review of preclinical and clinical studies

GF Meresman, M Götte… - Human reproduction …, 2021 - academic.oup.com
BACKGROUND Given the disadvantages and limitations of current endometriosis therapy,
there is a progressive increase in studies focusing on plant-derived agents as a natural …

Endometriosis: a disease with few direct treatment options

PRC França, ACP Lontra, PD Fernandes - Molecules, 2022 - mdpi.com
Endometriosis is a gynecological condition characterized by the growth of endometrium-like
tissues inside and outside the pelvic cavity. The evolution of the disease can lead to infertility …

Immunological basis of the endometriosis: the complement system as a potential therapeutic target

C Agostinis, A Balduit, A Mangogna, G Zito… - Frontiers in …, 2021 - frontiersin.org
Endometriosis (EM) is a chronic disease characterized by the presence and proliferation of
functional endometrial glands and stroma outside the uterine cavity. Ovaries and pelvic …