Platinum (Pt) compounds entered the clinic as anticancer agents when cisplatin was
approved in 1978. More than 40 years later, even in the era of precision medicine and …

Mesoporous silica nanoparticles (MSNPs) are a particular example of innovative
nanomaterials for the development of drug delivery systems. MSNPs have recently received …

Combination chemotherapy has become a treatment modality for breast cancer. However,
serious side effects and high cytotoxicity associated with this combination therapy make it a …

Glioblastoma is an incurable cancer with a 5-year survival chance of less than 5%.
Chemotherapy is a therapeutic approach to treating the disease; however, due to the …

Staphylococcus aureus (S. aureus) biofilm-associated infections are a primary concern for
public health worldwide. Current therapeutics cannot penetrate the biofilms efficiently …

This study aimed to evaluate the therapeutic efficacy of the cisplatin encapsulated into
polybutylcyanoacrylate (PBCA) nanoparticles for the treatment of kidney cancer. The …

Background: Drug delivery systems have demonstrated promising results to cross blood–
brain barrier (BBB) and deliver the loaded therapeutics to the brain tumor. This study aims to …

Camel milk is a valuable source of nutrition with a wide range of therapeutic effects. Its
unique composition helps to regulate the blood glucose level. The current study is aimed to …

Drug repositioning is defined as a process to identify a new application for drugs. This
approach is critical as it takes advantage of well-known pharmacokinetics …

Low water solubility and thus low bioavailability limit the clinical application of fenbendazole
(FBZ) as a potential anticancer drug. Solubilizing agents, such as Mobil Composition of …