Low water solubility and thus low bioavailability limit the clinical application of fenbendazole
(FBZ) as a potential anticancer drug. Solubilizing agents, such as Mobil Composition of …

This study aimed to characterize a stable nano-niosome formulation, which could reduce the
adverse effects of carboplatin (CB) and improve its therapeutic efficacy in the treatment of …

Advances in the development of anti-tumour drugs and related technologies have resulted
in a significant increase in the number of cancer survivors. However, the incidence of …

This study aimed to improve the water solubility and cutaneous permeability of Amphotericin
B (AmB) for the topical treatment of Leishmania major-induced cutaneous leishmaniasis …

(1) Background: Glioblastoma (GBM) is the most frequent cerebral tumor. It almost always
relapses and there is no validated treatment for second-line GBM. We proposed the …

Loss or dysfunction of the pancreatic beta cells or insulin receptors leads to diabetes
mellitus (DM). This usually occurs over many years; therefore, the development of methods …

Antimicrobial resistance is a major concern for public health throughout the world that
severely restricts available treatments. In this context, methicillin-resistant Staphylococcus …

Background Chemotherapy is still the main first-line treatment for advanced metastatic
gastric cancer, but it has the limitations of serious side effects and drug resistance …

Bioactive molecules and their effects have been influenced by their solubility and
administration route. In many therapeutic reagents, the performance of therapeutics is …

Thiabendazole (TBZ) is an anthelmintic drug currently studied for anticancer purposes.
However, due to its low solubility, its biomedical application has been limited. Using …