Understanding the physiology of human defaecation and disorders of continence and evacuation

PT Heitmann, PF Vollebregt, CH Knowles… - Nature reviews …, 2021 - nature.com
The act of defaecation, although a ubiquitous human experience, requires the coordinated
actions of the anorectum and colon, pelvic floor musculature, and the enteric, peripheral and …

Functional bowel disorders with diarrhoea: Clinical guidelines of the United European Gastroenterology and European Society for Neurogastroenterology and Motility

E Savarino, F Zingone, B Barberio… - United European …, 2022 - Wiley Online Library
Irritable bowel syndrome with diarrhoea (IBS‐D) and functional diarrhoea (FDr) are the two
major functional bowel disorders characterized by diarrhoea. In spite of their high …

British Society of Gastroenterology guidelines on the management of functional dyspepsia

CJ Black, PA Paine, A Agrawal, I Aziz, MP Eugenicos… - Gut, 2022 - gut.bmj.com
Functional dyspepsia (FD) is a common disorder of gut–brain interaction, affecting
approximately 7% of individuals in the community, with most patients managed in primary …

United European Gastroenterology (UEG) and European Society for Neurogastroenterology and Motility (ESNM) consensus on functional dyspepsia

L Wauters, R Dickman, V Drug, A Mulak… - …, 2021 - Wiley Online Library
Background Functional dyspepsia (FD) is one of the most common conditions in clinical
practice. In spite of its prevalence, FD is associated with major uncertainties in terms of its …

[HTML][HTML] Irritable bowel syndrome and mental health comorbidity—approach to multidisciplinary management

HM Staudacher, CJ Black, SB Teasdale… - Nature Reviews …, 2023 - nature.com
Irritable bowel syndrome (IBS) affects 5–10% of the global population. Up to one-third of
people with IBS also experience anxiety or depression. Gastrointestinal and psychological …

[HTML][HTML] Evidence-based clinical practice guidelines for irritable bowel syndrome 2020

S Fukudo, T Okumura, M Inamori, Y Okuyama… - Journal of …, 2021 - Springer
Managing irritable bowel syndrome (IBS) has attracted international attention because
single-agent therapy rarely relieves bothersome symptoms for all patients. The Japanese …

Post‐infection functional gastrointestinal disorders following coronavirus disease‐19: a case–control study

UC Ghoshal, U Ghoshal, MM Rahman… - Journal of …, 2022 - Wiley Online Library
Abstract Background and Aim Because acute infectious gastroenteritis may cause post‐
infection irritable bowel syndrome and functional dyspepsia and the severe acute respiratory …

Gastric dysfunction in patients with chronic nausea and vomiting syndromes defined by a noninvasive gastric mapping device

AA Gharibans, S Calder, C Varghese, S Waite… - Science translational …, 2022 - science.org
Chronic nausea and vomiting syndromes (NVSs) are prevalent and debilitating disorders.
Putative mechanisms include gastric neuromuscular disease and dysregulation of brain-gut …

Role of gut microbiota in functional constipation

S Zhang, R Wang, D Li, L Zhao… - Gastroenterology Report, 2021 - academic.oup.com
Functional constipation (FC) is common, yet the etiology is not clear. Accumulating evidence
suggests an association between FC and abnormal gut microbiota. The relationship …

[HTML][HTML] Irritable bowel syndrome and the gut microbiome: a comprehensive review

SD Shaikh, N Sun, A Canakis, WY Park… - Journal of Clinical …, 2023 - mdpi.com
Irritable Bowel Syndrome (IBS) is a functional disorder of the gastrointestinal tract
characterized by abdominal pain and altered bowel habits. It has a prevalence of 10 to 25 …