Background Irritable bowel syndrome (IBS) has been associated with diets rich in
fermentable oligo-, di-, monosaccharides, and polyols (FODMAPs), and gluten. Most …

Background Olorinab is a highly selective, peripherally acting, full agonist of cannabinoid
receptor 2. This study assessed the efficacy and safety of olorinab to treat abdominal pain in …

Background Little is known about associations with reduced quality of life in irritable bowel
syndrome (IBS) or impact of IBS on quality of life compared with other chronic conditions …

Many healthy people suffer from milk-related gastrointestinal discomfort (GID) despite not
being lactose intolerant; the mechanisms underpinning such condition are unknown. This …

The physiological consequences of stress often manifest in the gastrointestinal tract.
Traumatic or chronic stress is associated with widespread maladaptive changes throughout …

The large surfaces of gastrointestinal (GI) organs are well adapted to their diverse tasks of
selective nutritional uptake and defense against the external environment. To maintain a …

Background Electrogastrography (EGG) non‐invasively evaluates gastric function but has
not achieved common clinical adoption due to several technical limitations. Body Surface …

Background Functional gastroduodenal disorders include functional dyspepsia, chronic
nausea and vomiting syndromes, and gastroparesis. These disorders are common, but their …

Microbiota can significantly contribute to colorectal cancer initiation and development. It was
described that E. coli harbouring polyketide synthase (pks) genes can synthetize bacterial …

Background There is increasing evidence suggesting that open-label placebo (OLP) is an
effective treatment for several medical conditions defined by self-report. However, little is …