AKR1B10 is a human nicotinamide adenine dinucleotide phosphate (NADPH)-dependent
reductase belonging to the aldo-keto reductase (AKR) 1B subfamily. It catalyzes the …

Conclusions Our findings indicate that LINC00665 is involved in the NF‐κB signaling
activation in HCC cells and that the inflammatory LINC00665/PKR/NF‐κB loop plays …

Background Increasing studies have shown that circRNA is closely related to the
carcinogenesis and development of many cancers. However, biological functions and the …

Abstract Background MicroRNAs (miRNAs) and Twist1-induced epithelial-mesenchymal
transition (EMT) in cancer cell dissemination are well established, but the involvement of …

Lung cancer is the most frequently diagnosed malignancy and the leading source of cancer-
associated mortality. This kind of cancer has heterogeneous nature and is divided into two …

Breast cancer is the most common malignant tumor among women worldwide. Although
increasing evidence indicates that long noncoding RNAs (lncRNAs) play critical roles during …

Long noncoding RNAs (lncRNAs) play a key role in human cancer development;
nevertheless, the effect of lncRNA LINC00665 on the progression of gastric cancer (GC) still …

Gemcitabine is the first-line chemotherapy drug for cholangiocarcinoma (CCA), but acquired
resistance has been frequently observed in CCA patients. To search for potential long …

The chromobox (CBX) proteins mediate epigenetic gene silencing and have been
implicated in the cancer development. By analyzing eight CBX family members in TCGA …

Glioma is a brain cancer characterized by strong invasiveness with limited treatment options
and poor prognosis. Recently, dysregulation of long non-coding RNAs (lncRNAs) has …