Surfactant therapy for acute lung injury and acute respiratory distress syndrome

K Raghavendran, D Willson… - Critical care …, 2011 - criticalcare.theclinics.com
The extensive pulmonary alveolar and capillary networks make the lungs highly susceptible
to cell and tissue injury from pathogens or toxic environmental agents present either in the …

Glucocorticoids and acute lung injury

BT Thompson - Critical care medicine, 2003 - journals.lww.com
Objectives To describe hypothalamic-pituitary-adrenal (HPA) activation and the role of
glucocorticoids in immune modulation during critical illness, and to review clinical trials of …

Potential benefits of precise corticosteroids therapy for severe 2019-nCoV pneumonia

W Zhou, Y Liu, D Tian, C Wang, S Wang… - Signal transduction and …, 2020 - nature.com
Since last December, the outbreak of 2019-nCoV in Wuhan has caused ever-increasing
attention and public panic all over the world. Up to February 9, 2020, 40,171 patients had …

[HTML][HTML] Efficacy and safety of corticosteroids for persistent acute respiratory distress syndrome

National Heart, Lung, and Blood Institute … - … England Journal of …, 2006 - Mass Medical Soc
Background Persistent acute respiratory distress syndrome (ARDS) is characterized by
excessive fibroproliferation, ongoing inflammation, prolonged mechanical ventilation, and a …

Effect of prolonged methylprednisolone therapy in unresolving acute respiratory distress syndrome: a randomized controlled trial

GU Meduri, AS Headley, E Golden, SJ Carson… - Jama, 1998 - jamanetwork.com
Context.—No pharmacological therapeutic protocol has been found effective in modifying
the clinical course of acute respiratory distress syndrome (ARDS) and mortality remains …

Postinjury multiple organ failure: a bimodal phenomenon

FA Moore, A Sauaia, EE Moore… - Journal of Trauma …, 1996 - journals.lww.com
To better define the epidemiology of postinjury multiple organ failure (MOF), we
prospectively evaluated 457 high-risk trauma patients who survived more than 48 hours …

[图书][B] Lung surfactants: basic science and clinical applications

RH Notter - 2000 - api.taylorfrancis.com
Integrating basic and clinical research on the biophysical and physiological functions of
pulmonary surfactants, this practical reference presents thorough, cutting-edge coverage on …

Discrimination of infectious and noninfectious causes of early acute respiratory distress syndrome by procalcitonin

FM Brunkhorst, OK Eberhard… - Critical care medicine, 1999 - journals.lww.com
Objective: To test the sepsis marker procalcitonin (PCT) for its applicability to discriminate
between septic and nonseptic causes of acute respiratory distress syndrome (ARDS) …

Thirty years of clinical trials in acute respiratory distress syndrome

RC McIntyre Jr, EJ Pulido, DD Bensard… - Critical care …, 2000 - journals.lww.com
Conclusions Lung protective ventilator strategy is the first therapy found to improve outcome
in ARDS. Trials of prone ventilation and fluid restriction in ARDS and corticosteroids in late …

Clinical characteristics and outcomes of post-COVID-19 pulmonary fibrosis: A case-control study

S Farghaly, M Badedi, R Ibrahim, MH Sadhan… - Medicine, 2022 - journals.lww.com
Clinical characteristics and outcomes of post-COVID-19 pulmo... : Medicine Clinical
characteristics and outcomes of post-COVID-19 pulmonary fibrosis: A case-control study …