[HTML][HTML] The international WAO/EAACI guideline for the management of hereditary angioedema–the 2021 revision and update

M Maurer, M Magerl, S Betschel, W Aberer… - World Allergy …, 2022 - Elsevier
Hereditary Angioedema (HAE) is a rare and disabling disease for which early diagnosis and
effective therapy are critical. This revision and update of the global WAO/EAACI guideline on …

Summary and future of medicine for hereditary angioedema

L Ding, MJ Zhang, GW Rao - Drug discovery today, 2024 - Elsevier
Hereditary angioedema (HAE) is a rare autosomal genetic disease for which there are
currently nine FDA-approved drugs. This review summarizes drug treatments for HAE based …

Hereditary angioedema: a review of the current and evolving treatment landscape

SD Betschel, A Banerji, PJ Busse, DM Cohn… - The Journal of Allergy …, 2023 - Elsevier
Hereditary angioedema (HAE) is a rare disease characterized by sudden and often
unprovoked episodes of swelling that can be potentially life-threatening when it involves the …

[HTML][HTML] Lanadelumab in patients 2 to less than 12 years old with hereditary angioedema: results from the phase 3 SPRING study

M Maurer, WR Lumry, HH Li, E Aygören-Pürsün… - The Journal of Allergy …, 2024 - Elsevier
Background Symptoms of hereditary angioedema (HAE) often first occur during childhood,
and HAE attacks in children can be severe and substantially affect health-related quality of …

[HTML][HTML] Treatment of hereditary angioedema—single or multiple pathways to the rescue

A Valerieva, HJ Longhurst - Frontiers in Allergy, 2022 - frontiersin.org
Hereditary angioedema (HAE) is a rare disease caused by mutations in the SERPING1
gene. This results in deficient or dysfunctional C1 esterase inhibitor (C1-INH) and affects …

Network meta-analysis for indirect comparison of lanadelumab and berotralstat for the treatment of hereditary angioedema

M Watt, M Malmenäs, D Romanus… - Journal of …, 2023 - becarispublishing.com
Aim: With no head-to-head studies comparing the effectiveness of lanadelumab and
berotralstat for prevention of hereditary angioedema (HAE) attacks, this network meta …

Kallikrein inhibitors for angioedema: the progress of preclinical and early phase studies

H Farkas, Z Balla - Expert opinion on investigational drugs, 2024 - Taylor & Francis
Introduction Hereditary angioedema (HAE) is a rare genetic disorder characterized by
recurrent edema and predominantly caused by the dysregulation of the kinin-kallikrein …

[HTML][HTML] Long-term lanadelumab treatment improves health-related quality of life in patients with hereditary angioedema

WR Lumry, M Maurer, K Weller, MA Riedl… - Annals of Allergy …, 2023 - Elsevier
Background Hereditary angioedema (HAE) is associated with a substantial disease burden.
Lanadelumab reduced the HAE attack rate during 132 weeks of follow-up in the HELP open …

Patient‐level indirect treatment comparison of lanadelumab versus pdC1‐INH iv in hereditary angioedema patients: PATCH study

M Magerl, G Schiffhorst, L Fanter, G Müller, C Hirche… - Allergy, 2024 - Wiley Online Library
Background Hereditary angioedema (HAE) is an autosomal dominant inherited disease in
which patients suffer from local attacks primarily affecting skin and gastrointestinal tract, and …

Safety Aspects and Rational Use of Lanadelumab Injections in the Treatment of Hereditary Angioedema (HAE): Clinical Insights

E Petkova, V Yordanova, M Staevska… - Drug, Healthcare and …, 2022 - Taylor & Francis
Hereditary angioedema (HAE) is a rare genetic disorder characterized by recurrent
episodes of skin/mucosal swelling, and/or attacks of severe abdominal pain when it affects …