BACKGROUND Infertility and pregnancy loss are longstanding problems. Successful
fertilization and high-quality embryos are prerequisites for an ongoing pregnancy. Studies …

RNA—the primary product of the genome—is subject to various biological events during its
lifetime. During mammalian gametogenesis and early embryogenesis, germ cells and …

Oocyte maturation arrest, fertilization failure, and early embryonic arrest are important
causes of female infertility, whereas the genetic events that contribute to these processes …

After fertilization, sperm and oocyte fused and gave rise to a zygote which is the beginning of
a new life. Then the embryonic development is monitored and regulated precisely from the …

Developmental arrest in preimplantation embryos is one of the major causes of assisted
reproduction failure. It is briefly defined as a delay or a failure of embryonic development in …

Strategies to maximize individual fertility chances are constant requirements of ART. I n vitro
folliculogenesis may represent a valid option to create a large source of immature ovarian …

Oocyte maturation is vital to attain full competence required for fertilization and
embryogenesis. NLRP14 is preferentially expressed in mammalian oocytes and early …

Normal oocyte maturation is an important requirement for the success of human
reproduction, and defects in this process will lead to female infertility and repeated IVF/ICSI …

Maternal-effect genes (MEGs) play an important role in maintaining the survival and
development of mammalian embryos at the cleavage stage after fertilization. Despite long …

Preimplantation embryonic arrest is an important pathogenesis of female infertility, but little
is known about the genetic factors behind this phenotype. MEI4 is an essential protein for …