Therapeutic importance of kaempferol in the treatment of cancer through the modulation of cell signalling pathways
MY Qattan, MI Khan, SH Alharbi, AK Verma… - Molecules, 2022 - mdpi.com
Plant-derived flavonoids are considered natural nontoxic chemo-preventers and have been
widely studied for cancer treatment in recent decades. Mostly all flavonoid compounds show …
widely studied for cancer treatment in recent decades. Mostly all flavonoid compounds show …
Reprogramming of lipid metabolism in lung cancer: An overview with focus on EGFR-Mutated non-small cell lung cancer
K Eltayeb, S La Monica, M Tiseo, R Alfieri, C Fumarola - Cells, 2022 - mdpi.com
Lung cancer is the leading cause of cancer deaths worldwide. Most of lung cancer cases are
classified as non-small cell lung cancers (NSCLC). EGFR has become an important …
classified as non-small cell lung cancers (NSCLC). EGFR has become an important …
GSH-responsive nanoprodrug to inhibit glycolysis and alleviate immunosuppression for cancer therapy
X Liu, Y Li, K Wang, Y Chen, M Shi, X Zhang… - Nano Letters, 2021 - ACS Publications
Blocking energy metabolism of cancer cells and simultaneously stimulating the immune
system to perform immune attack are significant for cancer treatment. However, how to …
system to perform immune attack are significant for cancer treatment. However, how to …
Development and validation of a robust ferroptosis-related prognostic signature in lung adenocarcinoma
A Zhang, J Yang, C Ma, F Li, H Luo - Frontiers in Cell and …, 2021 - frontiersin.org
Background Lung adenocarcinoma (LUAD) is the most common subtype of non-small cell
lung cancer. Ferroptosis is a newly recognized process of cell death, which is different from …
lung cancer. Ferroptosis is a newly recognized process of cell death, which is different from …
Roles of lipid metabolism and its regulatory mechanism in idiopathic pulmonary fibrosis: A review
Y Tian, C Duan, J Feng, J Liao, Y Yang… - The International Journal of …, 2023 - Elsevier
Idiopathic pulmonary fibrosis is a progressive lung disease of unknown etiology
characterized by distorted distal lung architecture, inflammation, and fibrosis. Several lung …
characterized by distorted distal lung architecture, inflammation, and fibrosis. Several lung …
Prognostic implication of a metabolism-associated gene signature in lung adenocarcinoma
L He, J Chen, F Xu, J Li - Molecular Therapy-Oncolytics, 2020 - cell.com
Lung cancer is the most common cancer worldwide, leading to high mortality each year.
Metabolic pathways play a vital role in the initiation and progression of lung cancer. We …
Metabolic pathways play a vital role in the initiation and progression of lung cancer. We …
[HTML][HTML] Friend or foe? An unrecognized role of uric acid in cancer development and the potential anticancer effects of uric acid-lowering drugs
S Mi, L Gong, Z Sui - Journal of Cancer, 2020 - ncbi.nlm.nih.gov
In recent years, metabolic syndrome (Mets) has been a hot topic among medical scientists.
Mets has an intimate relationship with the incidence and development of various cancers. As …
Mets has an intimate relationship with the incidence and development of various cancers. As …
Comprehensive analysis of a novel signature incorporating lipid metabolism and immune-related genes for assessing prognosis and immune landscape in lung …
Y Wang, J Xu, Y Fang, J Gu, F Zhao, Y Tang… - Frontiers in …, 2022 - frontiersin.org
Background As the crosstalk between metabolism and antitumor immunity continues to be
unraveled, we aim to develop a prognostic gene signature that integrates lipid metabolism …
unraveled, we aim to develop a prognostic gene signature that integrates lipid metabolism …
Ubiquitination links DNA damage and repair signaling to cancer metabolism
SY Koo, EJ Park, HJ Noh, SM Jo, BK Ko… - International Journal of …, 2023 - mdpi.com
Changes in the DNA damage response (DDR) and cellular metabolism are two important
factors that allow cancer cells to proliferate. DDR is a set of events in which DNA damage is …
factors that allow cancer cells to proliferate. DDR is a set of events in which DNA damage is …
The role of MicroRNAs in lung cancer metabolism
Simple Summary Tumor cells exhibit dysregulation in metabolic activities compared with
normal cells. Lung cancer is one of the most commonly diagnosed cancers globally. Studies …
normal cells. Lung cancer is one of the most commonly diagnosed cancers globally. Studies …