We review theoretical and numerical models of the glymphatic system, which circulates
cerebrospinal fluid and interstitial fluid around the brain, facilitating solute transport. Models …

Biological tissues are fed by arterial networks whose task is to set blood flow delivery in
accordance with energetic demand. Coordinating vasomotor activity among hundreds of …

Rationale: Mutations in GJC2 and GJA1, encoding Cxs (connexins) 47 and 43, respectively,
are linked to lymphedema, but the underlying mechanisms are unknown. Because efficient …

To perform their functions, the kidneys maintain stable blood perfusion in the face of
fluctuations in systemic BP. This is done through autoregulation of blood flow by the generic …

Arterial tone is coordinated among vessel segments to optimize nutrient transport and organ
function. Coordinated vasomotor activity is remarkable to observe and depends on stimuli …

Contractions of lymphangions, ie, the segment between two one-way lymphatic valves,
generate the pressure gradients that propel lymph back to the circulation. Each lymphangion …

It is well established that the cerebral blood flow (CBF) shows exquisite sensitivity to
changes in the arterial blood partial pressure of CO 2 (P a, CO 2), which is reflected by an …

Regulation of renal vascular resistance plays a major role in controlling arterial blood
pressure. The endothelium participates in this regulation as endothelial derived …

We examined the roles played by gap junctions (GJs) and the GJ channel protein connexin
43 (Cx43) in arginine vasopressin (AVP)-induced vasoconstriction after hemorrhagic shock …

Highlights•MEGJ are differentially regulated dependent on their connexin
composition.•MEGJ are regulated through post-translational modifications of vascular …