Due to the key role of tumor necrosis factor-alpha (TNF-α) in the pathogenesis of
immunoinflammatory diseases, TNF-α inhibitors have been successfully developed and …

Abstract Purpose of Review To summarize experimental and clinical evidence on the
association between tumor necrosis factor-α (TNF-α) and nonalcoholic fatty liver disease …

Rheumatoid arthritis (RA) is a chronic and systemic autoimmune disease of unknown
etiology. The most common form of this disease is chronic inflammatory arthritis, which …

Coronary atherosclerosis is a chronic pathological process that involves inflammation
together with endothelial dysfunction and lipoprotein dysregulation. Experimental studies …

This review analyzes the role of TNF-α and its increase in biological fluids in mild cognitive
impairment, and Alzheimer's disease (AD). The potential inhibition of TNF-α with …

Objective To evaluate efficacy and safety of total glucosides of paeony in the treatment of 5
types of inflammatory arthritis Methods Databases such as Pubmed, Cochran Library …

Introduction: Tumor necrosis factor (TNF) inhibitors (adalimumab, infliximab, etanercept,
golimumab, and certolizumab pegol) have revolutionized the treatment of severe immune …

Inflammation is a dysregulated immune response characterized by an excessive release of
proinflammatory mediators, such as cytokines and prostanoids, leading to tissue damage …

Immune checkpoint inhibitors (ICIs) are effective therapies approved in multiple and
expanding oncologic indications. The mechanism of ICIs involves blocking immune …

Background Evidence for use of second-line immunosuppressants for immune-related
adverse events (irAEs) is inadequate. Therefore, a multicenter analysis should assess the …