[HTML][HTML] Past, present and (foreseeable) future of biological anti-TNF alpha therapy
GM Leone, K Mangano, MC Petralia, F Nicoletti… - Journal of Clinical …, 2023 - mdpi.com
Due to the key role of tumor necrosis factor-alpha (TNF-α) in the pathogenesis of
immunoinflammatory diseases, TNF-α inhibitors have been successfully developed and …
immunoinflammatory diseases, TNF-α inhibitors have been successfully developed and …
[HTML][HTML] The role of tumor necrosis factor-alpha in the pathogenesis and treatment of nonalcoholic fatty liver disease
ID Vachliotis, SA Polyzos - Current obesity reports, 2023 - Springer
Abstract Purpose of Review To summarize experimental and clinical evidence on the
association between tumor necrosis factor-α (TNF-α) and nonalcoholic fatty liver disease …
association between tumor necrosis factor-α (TNF-α) and nonalcoholic fatty liver disease …
[HTML][HTML] Rheumatoid arthritis: the old issue, the new therapeutic approach
M Babaahmadi, B Tayebi, NM Gholipour… - Stem Cell Research & …, 2023 - Springer
Rheumatoid arthritis (RA) is a chronic and systemic autoimmune disease of unknown
etiology. The most common form of this disease is chronic inflammatory arthritis, which …
etiology. The most common form of this disease is chronic inflammatory arthritis, which …
[HTML][HTML] The impact of cytokines in coronary atherosclerotic plaque: current therapeutic approaches
Coronary atherosclerosis is a chronic pathological process that involves inflammation
together with endothelial dysfunction and lipoprotein dysregulation. Experimental studies …
together with endothelial dysfunction and lipoprotein dysregulation. Experimental studies …
[HTML][HTML] The Role of TNF-α in Alzheimer's Disease: A Narrative Review
This review analyzes the role of TNF-α and its increase in biological fluids in mild cognitive
impairment, and Alzheimer's disease (AD). The potential inhibition of TNF-α with …
impairment, and Alzheimer's disease (AD). The potential inhibition of TNF-α with …
[HTML][HTML] Efficacy and safety of total glucosides of paeony in the treatment of 5 types of inflammatory arthritis: a systematic review and meta-analysis
K Yang, L Zeng, Z Long, Q He, W Xiang, A Ge… - Pharmacological …, 2023 - Elsevier
Objective To evaluate efficacy and safety of total glucosides of paeony in the treatment of 5
types of inflammatory arthritis Methods Databases such as Pubmed, Cochran Library …
types of inflammatory arthritis Methods Databases such as Pubmed, Cochran Library …
[HTML][HTML] Characteristic analysis of adverse reactions of five anti-TNFɑ agents: a descriptive analysis from WHO-VigiAccess
M Li, R You, Y Su, H Zhou, S Gong - Frontiers in Pharmacology, 2023 - frontiersin.org
Introduction: Tumor necrosis factor (TNF) inhibitors (adalimumab, infliximab, etanercept,
golimumab, and certolizumab pegol) have revolutionized the treatment of severe immune …
golimumab, and certolizumab pegol) have revolutionized the treatment of severe immune …
Potential Utilization of Phenolic Acid Compounds as Anti-Inflammatory Agents through TNF-α Convertase Inhibition Mechanisms: A Network Pharmacology, Docking …
Inflammation is a dysregulated immune response characterized by an excessive release of
proinflammatory mediators, such as cytokines and prostanoids, leading to tissue damage …
proinflammatory mediators, such as cytokines and prostanoids, leading to tissue damage …
[HTML][HTML] Accelerating the evolution of immune-related enterocolitis management
DM Faleck, M Dougan, M Tello… - Journal of Clinical …, 2023 - ncbi.nlm.nih.gov
Immune checkpoint inhibitors (ICIs) are effective therapies approved in multiple and
expanding oncologic indications. The mechanism of ICIs involves blocking immune …
expanding oncologic indications. The mechanism of ICIs involves blocking immune …
[HTML][HTML] Second-line immunosuppressant administration for steroid-refractory immune-related adverse events in patients with lung cancer
S Ogusu, Y Harutani, T Tozuka, R Saito… - Cancer Immunology …, 2023 - Springer
Background Evidence for use of second-line immunosuppressants for immune-related
adverse events (irAEs) is inadequate. Therefore, a multicenter analysis should assess the …
adverse events (irAEs) is inadequate. Therefore, a multicenter analysis should assess the …