The mammalian circulatory system comprises both the cardiovascular system and the
lymphatic system. In contrast to the blood vascular circulation, the lymphatic system forms a …

The lymphatic vasculature forms a vessel network that drains interstitial fluid from tissues
and returns it to the blood. Lymphatic vessels are also an essential part of the body's …

The blood–brain barrier (BBB) is formed primarily to protect the brain microenvironment from
the influx of plasma components, which may disturb neuronal functions. The BBB is a …

Studies of the last decades have revealed the importance of angiogenesis for normal growth
and for the pathogenesis of numerous diseases. Much less studied is lymphangiogenesis …

The WAVE regulatory complex (WRC) controls actin cytoskeletal dynamics throughout the
cell by stimulating the actin-nucleating activity of the Arp2/3 complex at distinct membrane …

Blood and lymphatic vessels develop in a parallel, but independent manner, and together
form the circulatory system allowing the passage of fluid and delivering molecules within the …

The lymphatic vascular system is important for immune surveillance, tissue fluid
homeostasis and fat absorption, and is involved in many pathological processes, including …

Lymphatic metastasis is the main prognostic factor for survival of patients with breast cancer
and other epithelial malignancies. Mounting clinical and experimental data suggest that …

The lymphatic vasculature is essential for the maintenance of tissue fluid balance, immune
surveillance, and adsorption fatty acids in the gut. The lymphatic vessels are also crucially …

▪ Abstract Cells adhere to the extracellular matrix throughout most of their lifetime. This close,
intimate contact with the matrix exerts an extraordinary control on the behavior of cells …