Obstacles and opportunities in a forward vision for cancer nanomedicine

I de Lázaro, DJ Mooney - Nature materials, 2021 - nature.com
Cancer nanomedicines were initially envisioned as magic bullets, travelling through the
circulation to target tumours while sparing healthy tissues the toxicity of classic …

[HTML][HTML] The ancillary effects of nanoparticles and their implications for nanomedicine

EP Stater, AY Sonay, C Hart, J Grimm - Nature Nanotechnology, 2021 - nature.com
Nanoparticles are often engineered as a scaffolding system to combine targeting, imaging
and/or therapeutic moieties into a unitary agent. However, mostly overlooked, the …

[HTML][HTML] Nanotechnology's frontier in combatting infectious and inflammatory diseases: prevention and treatment

Y Huang, X Guo, Y Wu, X Chen, L Feng, N Xie… - … and Targeted Therapy, 2024 - nature.com
Inflammation-associated diseases encompass a range of infectious diseases and non-
infectious inflammatory diseases, which continuously pose one of the most serious threats to …

[HTML][HTML] The interaction between nanoparticles and immune system: application in the treatment of inflammatory diseases

J Liu, Z Liu, Y Pang, H Zhou - Journal of Nanobiotechnology, 2022 - Springer
Nanoparticle (NP) is an emerging tool applied in the biomedical field. With combination of
different materials and adjustment of their physical and chemical properties, nanoparticles …

Understanding nanomaterial–liver interactions to facilitate the development of safer nanoapplications

J Li, C Chen, T Xia - Advanced Materials, 2022 - Wiley Online Library
Nanomaterials (NMs) are widely used in commercial and medical products, such as
cosmetics, vaccines, and drug carriers. Exposure to NMs via various routes such as dermal …

[HTML][HTML] Targeted modulation of immune cells and tissues using engineered biomaterials

P Yousefpour, K Ni, DJ Irvine - Nature reviews bioengineering, 2023 - nature.com
Therapies modulating the immune system offer the prospect of treating a wide range of
conditions including infectious diseases, cancer and autoimmunity. Biomaterials can …

Translational selenium nanoparticles to attenuate allergic dermatitis through Nrf2-Keap1-driven activation of selenoproteins

B Xie, D Zeng, M Yang, Z Tang, L He, T Chen - ACS nano, 2023 - ACS Publications
Easy recurrence and strong treatment side effects significantly limit the clinical treatment of
allergic dermatitis. The human trace element selenium (Se) plays essential roles in redox …

Use of a liver-targeting immune-tolerogenic mRNA lipid nanoparticle platform to treat peanut-induced anaphylaxis by single-and multiple-epitope nucleotide …

X Xu, X Wang, YP Liao, L Luo, T Xia, AE Nel - ACS nano, 2023 - ACS Publications
While oral desensitization is capable of alleviating peanut allergen anaphylaxis, long-term
immune tolerance is the sought-after goal. We developed a liver-targeting lipid nanoparticle …

Nanotoxicology and nanomedicine: The Yin and Yang of nano-bio interactions for the new decade

O Bondarenko, M Mortimer, A Kahru, N Feliu, I Javed… - Nano Today, 2021 - Elsevier
Nanotoxicology and nanomedicine are two sub-disciplines of nanotechnology focusing on
the phenomena, mechanisms, and engineering at the nano-bio interface. For the better part …

[HTML][HTML] The endothelium as a driver of liver fibrosis and regeneration

E Lafoz, M Ruart, A Anton, A Oncins, V Hernández-Gea - Cells, 2020 - mdpi.com
Liver fibrosis is a common feature of sustained liver injury and represents a major public
health problem worldwide. Fibrosis is an active research field and discoveries in the last …