Obstacles and opportunities in a forward vision for cancer nanomedicine
I de Lázaro, DJ Mooney - Nature materials, 2021 - nature.com
Cancer nanomedicines were initially envisioned as magic bullets, travelling through the
circulation to target tumours while sparing healthy tissues the toxicity of classic …
circulation to target tumours while sparing healthy tissues the toxicity of classic …
[HTML][HTML] The ancillary effects of nanoparticles and their implications for nanomedicine
Nanoparticles are often engineered as a scaffolding system to combine targeting, imaging
and/or therapeutic moieties into a unitary agent. However, mostly overlooked, the …
and/or therapeutic moieties into a unitary agent. However, mostly overlooked, the …
[HTML][HTML] Nanotechnology's frontier in combatting infectious and inflammatory diseases: prevention and treatment
Y Huang, X Guo, Y Wu, X Chen, L Feng, N Xie… - … and Targeted Therapy, 2024 - nature.com
Inflammation-associated diseases encompass a range of infectious diseases and non-
infectious inflammatory diseases, which continuously pose one of the most serious threats to …
infectious inflammatory diseases, which continuously pose one of the most serious threats to …
[HTML][HTML] The interaction between nanoparticles and immune system: application in the treatment of inflammatory diseases
J Liu, Z Liu, Y Pang, H Zhou - Journal of Nanobiotechnology, 2022 - Springer
Nanoparticle (NP) is an emerging tool applied in the biomedical field. With combination of
different materials and adjustment of their physical and chemical properties, nanoparticles …
different materials and adjustment of their physical and chemical properties, nanoparticles …
Understanding nanomaterial–liver interactions to facilitate the development of safer nanoapplications
Nanomaterials (NMs) are widely used in commercial and medical products, such as
cosmetics, vaccines, and drug carriers. Exposure to NMs via various routes such as dermal …
cosmetics, vaccines, and drug carriers. Exposure to NMs via various routes such as dermal …
[HTML][HTML] Targeted modulation of immune cells and tissues using engineered biomaterials
P Yousefpour, K Ni, DJ Irvine - Nature reviews bioengineering, 2023 - nature.com
Therapies modulating the immune system offer the prospect of treating a wide range of
conditions including infectious diseases, cancer and autoimmunity. Biomaterials can …
conditions including infectious diseases, cancer and autoimmunity. Biomaterials can …
Translational selenium nanoparticles to attenuate allergic dermatitis through Nrf2-Keap1-driven activation of selenoproteins
B Xie, D Zeng, M Yang, Z Tang, L He, T Chen - ACS nano, 2023 - ACS Publications
Easy recurrence and strong treatment side effects significantly limit the clinical treatment of
allergic dermatitis. The human trace element selenium (Se) plays essential roles in redox …
allergic dermatitis. The human trace element selenium (Se) plays essential roles in redox …
Use of a liver-targeting immune-tolerogenic mRNA lipid nanoparticle platform to treat peanut-induced anaphylaxis by single-and multiple-epitope nucleotide …
While oral desensitization is capable of alleviating peanut allergen anaphylaxis, long-term
immune tolerance is the sought-after goal. We developed a liver-targeting lipid nanoparticle …
immune tolerance is the sought-after goal. We developed a liver-targeting lipid nanoparticle …
Nanotoxicology and nanomedicine: The Yin and Yang of nano-bio interactions for the new decade
Nanotoxicology and nanomedicine are two sub-disciplines of nanotechnology focusing on
the phenomena, mechanisms, and engineering at the nano-bio interface. For the better part …
the phenomena, mechanisms, and engineering at the nano-bio interface. For the better part …
[HTML][HTML] The endothelium as a driver of liver fibrosis and regeneration
E Lafoz, M Ruart, A Anton, A Oncins, V Hernández-Gea - Cells, 2020 - mdpi.com
Liver fibrosis is a common feature of sustained liver injury and represents a major public
health problem worldwide. Fibrosis is an active research field and discoveries in the last …
health problem worldwide. Fibrosis is an active research field and discoveries in the last …