Global prevalence of depression in older adults: a systematic review and meta-analysis of epidemiological surveys
Background The reported prevalence of depressive symptoms (depression hereafter)
among older adults varied widely across different studies. This was a meta-analysis to …
among older adults varied widely across different studies. This was a meta-analysis to …
Association of inflammation with depression and anxiety: evidence for symptom-specificity and potential causality from UK Biobank and NESDA cohorts
Y Milaneschi, N Kappelmann, Z Ye, F Lamers… - Molecular …, 2021 - nature.com
We examined whether inflammation is uniformly associated with all depressive and anxiety
symptoms, and whether these associations are potentially causal. Data was from 147,478 …
symptoms, and whether these associations are potentially causal. Data was from 147,478 …
A role of gut–microbiota–brain axis via subdiaphragmatic vagus nerve in depression-like phenotypes in Chrna7 knock-out mice
The α7 subtype of the nicotinic acetylcholine receptor (α7 nAChR: coded by Chrna7) is
known to regulate the cholinergic ascending anti-inflammatory pathway. We previously …
known to regulate the cholinergic ascending anti-inflammatory pathway. We previously …
Inflammation and depression in young people: a systematic review and proposed inflammatory pathways
Depression onset peaks during adolescence and young adulthood. Current treatments are
only moderately effective, driving the search for novel pathophysiological mechanisms …
only moderately effective, driving the search for novel pathophysiological mechanisms …
Inflammation, stress and depression: an exploration of ketamine's therapeutic profile
Highlights•Chronic stress, depression and inflammation have been consistently
linked.•Stress-induced inflammatory states can contribute to treatment resistance.•Ketamine …
linked.•Stress-induced inflammatory states can contribute to treatment resistance.•Ketamine …
The immune profile of major dysmood disorder: proof of concept and mechanism using the precision nomothetic psychiatry approach
Major depressive disorder and a major depressive episode (MDD/MDE) are characterized
by activation of the immune-inflammatory response system (IRS) and the compensatory …
by activation of the immune-inflammatory response system (IRS) and the compensatory …
Aiding and abetting anhedonia: impact of inflammation on the brain and pharmacological implications
Exogenous administration of inflammatory stimuli to humans and laboratory animals and
chronic endogenous inflammatory states lead to motivational deficits and ultimately …
chronic endogenous inflammatory states lead to motivational deficits and ultimately …
Obesity and psychological distress
The relationship between high body weight and mental health has been studied for several
decades. Improvements in the quality of epidemiological, mechanistic and psychological …
decades. Improvements in the quality of epidemiological, mechanistic and psychological …
[HTML][HTML] The future is dynamic: a call for intensive longitudinal data in immunopsychiatry
DP Moriarity, GM Slavich - Brain, behavior, and immunity, 2023 - Elsevier
The long-term value of immunopsychiatry will be based on its ability to translate basic
science into effective clinical interventions. In this article, we discuss a key obstacle to …
science into effective clinical interventions. In this article, we discuss a key obstacle to …