Estimating the rates at which bacterial genomes evolve is critical to understanding major
evolutionary and ecological processes such as disease emergence, long-term host …

Helicobacter pylori, a member of Epsilonproteobacteria, is a Gram-negative microaerophilic
bacterium that colonizes gastric mucosa of about 50% of the human population. Although …

Helicobacter pylori colonizes the gastric epithelial cells of at least half of the world's
population, and it is the strongest risk factor for developing gastric complications like chronic …

Microbial archaeology is flourishing in the era of high-throughput sequencing, revealing the
agents behind devastating historical plagues, identifying the cryptic movements of …

Ancient DNA research has been revolutionized following development of next-generation
sequencing platforms. Although a number of such platforms have been applied to ancient …

Infection with Helicobacter pylori (H. pylori) is necessary but not sufficient for the
development of gastric cancer, the third leading cause of cancer death globally. H. pylori …

Helicobacter pylori (H. pylori) is transmitted primarily through the oral–oral route and fecal–
oral route. The oral cavity had therefore been hypothesized as an extragastric reservoir of H …

While a comparatively young area of research, investigations relying on ancient DNA data
have been highly valuable in revealing snapshots of genetic variation in both the recent and …

Abstract The hygiene or “Old Friends” hypothesis proposes that the epidemic of
inflammatory disease in modern urban societies stems at least in part from reduced …

Highly virulent Helicobacter pylori cause proinflammatory signaling inducing the
transcriptional activation and secretion of cytokines such as IL-8 in epithelial cells …