The role of vascular cells during inflammation is critical and is of particular importance in
inflammatory diseases, including atherosclerosis, ischemia/reperfusion, and septic shock …

The central role of vascular endothelial growth factor (VEGF) in angiogenesis in health and
disease makes it attractive both as a therapeutic target for anti-angiogenic drugs and as a …

The role of angiogenesis in atherosclerosis and other cardiovascular diseases has emerged
as a major unresolved issue. Angiogenesis has attracted interest from opposite …

OBJECTIVE—The expansion of adipose tissue mass seen in obesity involves both
hyperplasia and hypertrophy of adipocytes. However, little is known about how adipocytes …

The role of preexisting collateral channels in the heart is far less well established. Early
studies failed to show the existence of coronary-to-coronary artery connection in normal …

Over the past decade, extensive research has focused on identifying the molecular
mechanisms and signal transduction pathways involved in the modulation of vascular …

Vascular endothelial growth factor (VEGF) is essential for angiogenesis in health and
pathophysiology, and it is currently a major focus for drug targeting in the development of …

Abstract Cyclooxygenase-2 (COX-2) is an immediate early response gene that can be
induced by a variety of tumor promoters, cytokines, growth factors and hypoxia. COX-2 …

Stroke is an acute cerebrovascular disease caused by ruptured or blocked blood vessels.
For the prevention of ischemic stroke, the coagulation state of blood and cerebrovascular …

Background—Vascular damage caused by cerebral ischemia leads to edema, hemorrhage
formation, and worsened outcomes in ischemic stroke patients. Therapeutic interventions …