The serum anion gap in the evaluation of acid-base disorders: what are its limitations and can its effectiveness be improved?

JA Kraut, GT Nagami - Clinical Journal of the American Society of …, 2013 - journals.lww.com
The serum anion gap has been utilized to identify errors in the measurement of electrolytes,
to detect paraproteins, and, most relevant to the nephrologist, to evaluate patients with …

Anion gap as a prognostic tool for risk stratification in critically ill patients–a systematic review and meta-analysis

SA Glasmacher, W Stones - BMC anesthesiology, 2015 - Springer
Background Lactate concentration is a robust predictor of mortality but in many low resource
settings facilities for its analysis are not available. Anion gap (AG), calculated from clinical …

Derivation and validation of the acute organ failure score to predict outcome in critically ill patients: a cohort study

KM Elias, T Moromizato, FK Gibbons… - Critical care …, 2015 - journals.lww.com
Objectives: Prediction models for ICU mortality rely heavily on physiologic variables that may
not be available in large retrospective studies. An alternative approach when physiologic …

Retrospective evaluation of the prognostic utility of plasma lactate concentration, base deficit, pH, and anion gap in canine and feline emergency patients

CJ Kohen, K Hopper, PH Kass… - Journal of Veterinary …, 2018 - Wiley Online Library
Objective To determine the association of plasma lactate concentration, pH, base deficit
(BD), and anion gap (AG) in dogs and cats on presentation to an emergency room with …

Pulmonary Infection Is an Independent Risk Factor for Long‐Term Mortality and Quality of Life for Sepsis Patients

XL He, XL Liao, ZC Xie, L Han… - BioMed Research …, 2016 - Wiley Online Library
Background. Long‐term outcomes (mortality and health‐related quality of life) of sepsis have
risen as important indicators for health care. Pulmonary infection and abdominal infection …

The association between serum anion gap and all‐cause mortality of unselected adult patients: A retrospective cohort study of> 20,000 patients

X Ji, S Peng - Journal of Clinical Laboratory Analysis, 2023 - Wiley Online Library
Background Even though the serum anion gap (AG) is frequently measured in clinical
practice, there is not much research that has examined long‐term mortality in unselected …

Association between delta anion gap and hospital mortality for patients in cardiothoracic surgery recovery unit: a retrospective cohort study

K Xie, C Zheng, GM Wang, YF Diao, C Luo, E Wang… - BMC surgery, 2022 - Springer
Backgrounds High level of anion gap (AG) was associated with organic acidosis. This study
aimed to explore the relationship between delta AG (ΔAG= AGmax− AGmin) during first 3 …

Metabolic acidosis and the role of unmeasured anions in critical illness and injury

T Zingg, B Bhattacharya, LL Maerz - Journal of Surgical Research, 2018 - Elsevier
Acid–base disorders are frequently present in critically ill patients. Metabolic acidosis is
associated with increased mortality, but it is unclear whether as a marker of the severity of …

Serum anion gap is predictive of mortality in an elderly population

SY Ahn, J Ryu, SH Baek, JW Han, JH Lee, S Ahn… - Experimental …, 2014 - Elsevier
An elevated serum anion gap is known to be associated with hypertension, low
cardiorespiratory fitness, and decreased renal function. We evaluated whether serum AG …

[HTML][HTML] Quantitative relationships among plasma lactate, inorganic phosphorus, albumin, unmeasured anions and the anion gap in lactic acidosis

J Figge, R Bellomo, M Egi - Journal of critical care, 2018 - Elsevier
Background Quantitative relationships among plasma [Lactate],[Pi],[Albumin], unmeasured
anions ([UA]) and the anion gap (AG K) in lactic acidosis (LA) are not well defined. Methods …