MOLPRINT 2D-based identification and synthesis of novel chromene based small molecules that target PLA2: validation through chemo-and bioinformatics …
Phospholipase A2 (PLA2) is known to regulate inflammation and hence it is considered as a
validated drug-target by medicinal chemists. In this report, we have identified and …
validated drug-target by medicinal chemists. In this report, we have identified and …
[PDF][PDF] 磷脂酶A2 亚型及其与男性生殖相关性研究
谢海锋， 李坤， 倪崖 - 2013 - researchgate.net
摘要磷脂酶A2 (phospholipase A2, PLA2) 是参与细胞代谢活动, 信号转导等过程的重要酶类之
一, 广泛分布于哺乳动物机体内. 随着对磷脂酶A2 研究的深入, 目前已有30 余种磷脂酶A2 …
一, 广泛分布于哺乳动物机体内. 随着对磷脂酶A2 研究的深入, 目前已有30 余种磷脂酶A2 …
[HTML][HTML] Thematic Review Series: Phospholipases: Central Role in Lipid Signaling and Disease: A new era of secreted phospholipase A2
M Murakami, H Sato, Y Miki, K Yamamoto… - Journal of Lipid …, 2015 - ncbi.nlm.nih.gov
Among more than 30 members of the phospholipase A 2 (PLA 2) superfamily, secreted PLA
2 (sPLA 2) enzymes represent the largest family, being Ca 2+-dependent low-molecular …
2 (sPLA 2) enzymes represent the largest family, being Ca 2+-dependent low-molecular …
Metabolic signatures in follicular fluid from human ovarian follicles during growth progression reveals that LPC as a predictor of follicular development and ovarian …
J hong Yang, Y Li, S Li, Y Zhang, R Feng, R Huang… - Authorea …, 2024 - techrxiv.org
Objective To investigate the metabolic characteristics of follicular fluid (FF) from human
ovarian follicles of different developmental stages, and whether there are metabolic …
ovarian follicles of different developmental stages, and whether there are metabolic …
Differential effects of sPLA2-GV and GX on cellular proliferation and lipid accumulation in HT29 colon cancer cells
Abstract Secretory phospholipase A 2 (sPLA 2) group of enzymes have been shown to
hydrolyze phospholipids, among which sPLA 2 Group V (GV) and Group X (GX) exhibit high …
hydrolyze phospholipids, among which sPLA 2 Group V (GV) and Group X (GX) exhibit high …
Lipid droplets are required for lipid mediator production and cancer cell proliferation
EJ Jovičić, AP Janež, TO Eichmann, V Brglez… - bioRxiv, 2021 - biorxiv.org
Lipid droplets are dynamic organelles with a central role in fatty acid metabolism. They
protect cells from lipotoxicity by sequestering excess fatty acids but also provide fatty acids …
protect cells from lipotoxicity by sequestering excess fatty acids but also provide fatty acids …
Патогенетическая роль изменений фосфолипидного и перекисного статуса эякулята при нарушении фертильности у мужчин
АА Кошмелев - 2012 - static.freereferats.ru
Актуальность проблемы. Характерной чертой демографической ситуации в России в
последние 15 лет является систематическая убыль абсолютной численности …
последние 15 лет является систематическая убыль абсолютной численности …
The genetic architecture of Secretory PLA2 (sPLA2) genes and their impact on sPLA2 activity/mass and association with CHD risk.
HJ Exeter - 2012 - discovery.ucl.ac.uk
Secretory phospholipase A2 group (sPLA2) enzymes hydrolyze the sn-2 ester bond of
phospholipids, producing lysophospholipids and free fatty acids. SPLA2s have been …
phospholipids, producing lysophospholipids and free fatty acids. SPLA2s have been …
Novel insights into the function and regulation of group X secretory phospholipase A2
JD Layne Jr - 2013 - uknowledge.uky.edu
Group X secretory phospholipase A 2 (GX sPLA 2) hydrolyzes membrane phospholipids
producing free fatty acids and lysophospholipids. Previous studies from our lab suggest that …
producing free fatty acids and lysophospholipids. Previous studies from our lab suggest that …
[图书][B] The Role of Secretory Phospholipase A2 Group IIA in Obesity and Metabolism
MS Kuefner - 2019 - search.proquest.com
Secretory phospholipase A 2 group IIA (PLA2G2A) is a member of a family of secretory
phospholipases previously implicated in inflammation, atherogenesis, and antibacterial …
phospholipases previously implicated in inflammation, atherogenesis, and antibacterial …