Next-generation sequencing technology: current trends and advancements
H Satam, K Joshi, U Mangrolia, S Waghoo, G Zaidi… - Biology, 2023 - mdpi.com
Simple Summary Next-generation sequencing (NGS) is a powerful tool used in genomics
research. NGS can sequence millions of DNA fragments at once, providing detailed …
research. NGS can sequence millions of DNA fragments at once, providing detailed …
Next-Generation sequencing transforming clinical practice and precision medicine
D Yadav, B Patil-Takbhate, A Khandagale… - Clinica Chimica …, 2023 - Elsevier
Next-generation sequencing (NGS) has revolutionized the field of genomics and is rapidly
transforming clinical diagnosis and precision medicine. This advanced sequencing …
transforming clinical diagnosis and precision medicine. This advanced sequencing …
Single-cell analysis of the epitranscriptome: RNA modifications under the microscope
E Crespo-García, A Bueno-Costa, M Esteller - RNA biology, 2024 - Taylor & Francis
The identification of mechanisms capable of modifying genetic information by the addition of
covalent RNA modifications distinguishes a level of complexity in gene expression which …
covalent RNA modifications distinguishes a level of complexity in gene expression which …
Identification of co-expressed gene networks promoting CD8+ T cell infiltration and having prognostic value in uveal melanoma
C Zhang, J Xiao, L Fa, F Jiang, H Jiang, L Zhou… - BMC …, 2023 - Springer
Current immunotherapies are unsatisfactory against uveal melanoma (UM); however,
elevated CD8+ T cell infiltration level indicates poor prognosis in UM. Here, we aimed to …
elevated CD8+ T cell infiltration level indicates poor prognosis in UM. Here, we aimed to …
Transcriptomic analysis of Vibrio alginolyticus challenged by Rhizoma coptidis reveals mechanisms of virulence genes
Z Zhu, XJ Xu, J Huang, G Xu, SC Liu, F Hong, Y Chen… - Gene, 2024 - Elsevier
Rhizoma coptidis, a Chinese herbal medicine widely used to treat various bacterial
infections, has the potential to develop antibiotic substitutes to overcome the drug resistance …
infections, has the potential to develop antibiotic substitutes to overcome the drug resistance …
[HTML][HTML] The Role of Biomarkers in HPV-Positive Head and Neck Squamous Cell Carcinoma: Towards Precision Medicine
Head and neck cancer (HNC) represents a significant global health challenge, with
squamous cell carcinomas (SCCs) accounting for approximately 90% of all HNC cases …
squamous cell carcinomas (SCCs) accounting for approximately 90% of all HNC cases …
Exposure to Mycotoxin Citrinin Promotes Carcinogenic Potential of Human Renal Cells
JF Tsai, TS Wu, YT Huang, WJ Lin… - Journal of Agricultural …, 2023 - ACS Publications
Mycotoxin citrinin (CTN), commonly found in food and health supplements, may induce
chromosomal instability. In this study, human renal proximal tubule epithelial cells …
chromosomal instability. In this study, human renal proximal tubule epithelial cells …
Comparative case study on NAMs: towards enhancing specific target organ toxicity analysis
Traditional risk assessment methodologies in toxicology have relied upon animal testing,
despite concerns regarding interspecies consistency, reproducibility, costs, and ethics. New …
despite concerns regarding interspecies consistency, reproducibility, costs, and ethics. New …
reanalyzerGSE: tackling the everlasting lack of reproducibility and reanalyses in transcriptomics
In the current context of transcriptomics democratization, there is an unprecedented surge in
the number of studies and datasets. However, advances are hampered by aspects such as …
the number of studies and datasets. However, advances are hampered by aspects such as …
Transcriptome Analysis of Compensatory Growth and Meat Quality Alteration after Varied Restricted Feeding Conditions in Beef Cattle
T Deng, M Liang, L Du, K Li, J Li, L Qian, Q Xue… - International Journal of …, 2024 - mdpi.com
Compensatory growth (CG) is a physiological response that accelerates growth following a
period of nutrient limitation, with the potential to improve growth efficiency and meat quality …
period of nutrient limitation, with the potential to improve growth efficiency and meat quality …