Brain derived neurotrophic factor (BDNF) has multiple biological functions which are
mediated by the activation of two receptors, tropomyosin receptor kinase B (TrkB) receptor …

Altered neurogenesis is suggested to be involved in the onset of brain diseases, including
mental disorders and neurodegenerative diseases. Neurotrophic factors are well known for …

Background: Current interventions for major depressive disorder (MDD) are suboptimal, and
only one third respond to them on initial treatment. Neuroplasticity theories are the basis for …

Neurotrophins including brain-derived neurotrophic factor, BDNF, have critical roles in
neuronal differentiation, cell survival, and synaptic function in the peripheral and central …

WITHDRAWN: Adult hippocampal neurogenesis and antidepressants effects - ScienceDirect
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Newborn neurons in the adult hippocampus are regulated by many intrinsic and extrinsic
cues. It is well accepted that elevated glucocorticoid levels lead to downregulation of adult …

Neurogenesis is currently an area of great interest in neuroscience. It is closely linked to
brain diseases, including mental disorders and neurodevelopmental disease. Both …

Major depressive disorder (MDD) is a heterogeneous psychiatric disease characterized by
persistent low mood, diminished interests, and impaired cognitive and social functions. The …

Lead is a heavy metal pollutant that is widely present in the environment. It affects every
organ system, yet the nervous system appears to be the most sensitive and primary target …

Alzheimer's disease is a prevalent form of dementia among elderly individuals and is
characterized by irreversible neurodegeneration. Despite extensive research, the exact …