Nitric oxide acts as a cotransmitter in a subset of dopaminergic neurons to diversify memory dynamics

Y Aso, RP Ray, X Long, D Bushey, K Cichewicz… - Elife, 2019 - elifesciences.org
Animals employ diverse learning rules and synaptic plasticity dynamics to record temporal
and statistical information about the world. However, the molecular mechanisms underlying …

Aversion and attraction through olfaction

Q Li, SD Liberles - Current Biology, 2015 - cell.com
Sensory cues that predict reward or punishment are fundamental drivers of animal behavior.
For example, attractive odors of palatable food or a potential mate predict reward, while …

[HTML][HTML] A neuronal mechanism controlling the choice between feeding and sexual behaviors in Drosophila

SJ Cheriyamkunnel, S Rose, PF Jacob, LA Blackburn… - Current Biology, 2021 - cell.com
Animals must express the appropriate behavior that meets their most pressing physiological
needs and their environmental context. However, it is currently unclear how alternative …

Insects have the capacity for subjective experience

C Klein, AB Barron - Animal Sentience, 2016 - wellbeingintlstudiesrepository.org
To what degree are non-human animals conscious? We propose that the most meaningful
way to approach this question is from the perspective of functional neurobiology. Here we …

A higher brain circuit for immediate integration of conflicting sensory information in Drosophila

LPC Lewis, KP Siju, Y Aso, AB Friedrich, AJB Bulteel… - Current biology, 2015 - cell.com
Animals continuously evaluate sensory information to decide on their next action. Different
sensory cues, however, often demand opposing behavioral responses. How does the brain …

Neural Circuits Underlying Behavioral Flexibility: Insights From Drosophila

AV Devineni, KM Scaplen - Frontiers in Behavioral Neuroscience, 2022 - frontiersin.org
Behavioral flexibility is critical to survival. Animals must adapt their behavioral responses
based on changes in the environmental context, internal state, or experience. Studies in …

Heterogeneity in striatal dopamine circuits: Form and function in dynamic reward seeking

AL Collins, BT Saunders - Journal of neuroscience research, 2020 - Wiley Online Library
The striatal dopamine system has long been studied in the context of reward learning,
motivation, and movement. Given the prominent role dopamine plays in a variety of adaptive …

Regulation of starvation-induced hyperactivity by insulin and glucagon signaling in adult Drosophila

Y Yu, R Huang, J Ye, V Zhang, C Wu, G Cheng, J Jia… - Elife, 2016 - elifesciences.org
Starvation induces sustained increase in locomotion, which facilitates food localization and
acquisition and hence composes an important aspect of food-seeking behavior. We …

Conceptual learning by miniature brains

A Avarguès-Weber, M Giurfa - Proceedings of the …, 2013 - royalsocietypublishing.org
Concepts act as a cornerstone of human cognition. Humans and non-human primates learn
conceptual relationships such as 'same','different','larger than','better than', among others. In …

[HTML][HTML] Driver lines for studying associative learning in Drosophila

Y Shuai, M Sammons, G Sterne, K Hibbard, H Yang… - eLife, 2024 - elifesciences.org
The mushroom body (MB) is the center for associative learning in insects. In Drosophila,
intersectional split-GAL4 drivers and electron microscopy (EM) connectomes have laid the …