Despite strong epidemiologic evidence linking respiratory virus infection to exacerbations of
chronic obstructive pulmonary disease, many of the cellular and molecular mechanisms by …

A vicious circle of infection and inflammation in the airways in chronic obstructive pulmonary
disease (COPD) could cause progressive lung damage and contribute to progressive loss of …

Airway viral infections are associated with the pathogenesis of asthma and COPD. It has
been argued that respiratory syncytial virus (RSV) infection in infancy is a probable causal …

Cif (PA2934), a bacterial virulence factor secreted in outer membrane vesicles by
Pseudomonas aeruginosa, increases the ubiquitination and lysosomal degradation of some …

Although respiratory syncytial virus (RSV) was discovered> 40 years ago, treatment remains
largely supportive. There are no safe and effective vaccines or specific treatments other than …

Interleukin-6 (IL-6) is a proinflammatory cytokine up-regulated by rhinovirus infection during
acute exacerbations of asthma and chronic obstructive pulmonary disease. The role of IL-6 …

The role of infection in chronic obstructive pulmonary disease (COPD) was first postulated in
1953 by Stuart-Harris and colleagues 1 in what is now known as the British hypothesis. They …

Objectives Respiratory syncytial virus (RSV) causes substantial morbidity and mortality in
older adults. We assessed severe clinical outcomes among hospitalized adults that were …

Respiratory syncytial virus (RSV) is the most common respiratory pathogen in infants and
young children. The pathophysiology of this infection in the respiratory system has been …

COPD (chronic obstructive pulmonary disease) is the most common pulmonary disease and
is the only common cause of death in which mortality is presently rising. It is caused by the …