Paracrine mechanisms of mesenchymal stem cells in tissue repair
M Gnecchi, P Danieli, G Malpasso… - Mesenchymal Stem Cells …, 2016 - Springer
Tissue regeneration from transplanted mesenchymal stromal cells (MSC) either through
transdifferentiation or cell fusion was originally proposed as the principal mechanism …
transdifferentiation or cell fusion was originally proposed as the principal mechanism …
Trophic effects of mesenchymal stem cells in tissue regeneration
Mesenchymal stem cells (MSCs) are considered to hold great therapeutic value for cell-
based therapy and for tissue regeneration in particular. Recent evidence indicates that the …
based therapy and for tissue regeneration in particular. Recent evidence indicates that the …
[HTML][HTML] Practical recommendations for long-term management of modifiable risks in kidney and liver transplant recipients: a guidance report and clinical checklist by …
JM Neuberger, WO Bechstein, DRJ Kuypers… - …, 2017 - journals.lww.com
Short-term patient and graft outcomes continue to improve after kidney and liver
transplantation, with 1-year survival rates over 80%; however, improving longer-term …
transplantation, with 1-year survival rates over 80%; however, improving longer-term …
Pathophysiology of ischemic acute kidney injury
AA Sharfuddin, BA Molitoris - Nature Reviews Nephrology, 2011 - nature.com
Acute kidney injury (AKI) as a consequence of ischemia is a common clinical event leading
to unacceptably high morbidity and mortality, development of chronic kidney disease (CKD) …
to unacceptably high morbidity and mortality, development of chronic kidney disease (CKD) …
Microvesicles derived from human adult mesenchymal stem cells protect against ischaemia–reperfusion-induced acute and chronic kidney injury
Background. Several studies demonstrated that mesenchymal stem cells (MSCs) reverse
acute kidney injury (AKI) by a paracrine mechanism rather than by MSC transdifferentiation …
acute kidney injury (AKI) by a paracrine mechanism rather than by MSC transdifferentiation …
[HTML][HTML] Microvesicles derived from mesenchymal stem cells enhance survival in a lethal model of acute kidney injury
S Bruno, C Grange, F Collino, MC Deregibus… - PloS one, 2012 - journals.plos.org
Several studies demonstrated that treatment with mesenchymal stem cells (MSCs) reduces
cisplatin mortality in mice. Microvesicles (MVs) released from MSCs were previously shown …
cisplatin mortality in mice. Microvesicles (MVs) released from MSCs were previously shown …
Bone marrow stromal cells attenuate sepsis via prostaglandin E2–dependent reprogramming of host macrophages to increase their interleukin-10 production
Sepsis causes over 200,000 deaths yearly in the US; better treatments are urgently needed.
Administering bone marrow stromal cells (BMSCs—also known as mesenchymal stem cells) …
Administering bone marrow stromal cells (BMSCs—also known as mesenchymal stem cells) …
Mesenchymal stem cell-derived microvesicles protect against acute tubular injury
S Bruno, C Grange, MC Deregibus… - Journal of the …, 2009 - journals.lww.com
Administration of mesenchymal stem cells (MSCs) improves the recovery from acute kidney
injury (AKI). The mechanism may involve paracrine factors promoting proliferation of …
injury (AKI). The mechanism may involve paracrine factors promoting proliferation of …
Mesenchymal stromal cells: current understanding and clinical status
HK Salem, C Thiemermann - Stem cells, 2010 - academic.oup.com
Multipotent mesenchymal stromal cells (MSCs) represent a rare heterogeneous subset of
pluripotent stromal cells that can be isolated from many different adult tissues that exhibit the …
pluripotent stromal cells that can be isolated from many different adult tissues that exhibit the …
Adult mesenchymal stem cells for tissue engineering versus regenerative medicine
AI Caplan - Journal of cellular physiology, 2007 - Wiley Online Library
Adult mesenchymal stem cells (MSCs) can be isolated from bone marrow or marrow
aspirates and because they are culture‐dish adherent, they can be expanded in culture …
aspirates and because they are culture‐dish adherent, they can be expanded in culture …