Simple Summary This study explores hypoxia-inducible factors (HIFs) in glioblastoma
development, progression, and treatment. Reviewing 104 relevant studies, it highlights …

As the deadliest type of primary brain tumor, gliomas represent a significant worldwide
health concern. Circular RNA (circRNA), a unique non-coding RNA molecule, seems to be …

Context Glioma, the most common primary malignant brain tumour, is a grave health
concern associated with high morbidity and mortality. Current treatments, while effective to …

Glioblastoma (GBM) poses a formidable challenge in oncology due to its aggressive nature
and dismal prognosis, with average survival rates around 15 months despite conventional …

Glioblastoma multiforme (GBM) is one of the most aggressive forms of brain tumor,
characterized by a daunting prognosis with a life expectancy hovering around 12–16 …

Glioblastoma, a formidable brain cancer, has remained a therapeutic challenge due to its
aggressive nature and resistance to conventional treatments. Recent data indicate that …

Glioblastoma is the most aggressive tumor in the central nervous system, with a survival rate
of less than 15 months despite multimodal therapy. Tumor recurrence frequently occurs after …

Ferroptosis, an iron-dependent form of non-apoptotic regulated cell death, is induced by the
accumulation of lipid peroxides on cellular membranes. Over the past decade, ferroptosis …