Advances in research on immunocyte iron metabolism, ferroptosis, and their regulatory roles in autoimmune and autoinflammatory diseases
L Zeng, K Yang, G Yu, W Hao, X Zhu, A Ge… - Cell Death & …, 2024 - nature.com
Autoimmune diseases commonly affect various systems, but their etiology and pathogenesis
remain unclear. Currently, increasing research has highlighted the role of ferroptosis in …
remain unclear. Currently, increasing research has highlighted the role of ferroptosis in …
[HTML][HTML] Microglia depletion reduces human neuronal APOE4-driven pathologies in a chimeric Alzheimer's disease model
A Rao, N Chen, MJ Kim, J Blumenfeld, O Yip, Y Hao… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Despite strong evidence supporting the involvement of both apolipoprotein E4 (APOE4) and
microglia in Alzheimer's Disease (AD) pathogenesis, the effects of microglia on neuronal …
microglia in Alzheimer's Disease (AD) pathogenesis, the effects of microglia on neuronal …
[HTML][HTML] Inflammatory Alterations to Renal Lymphatic Endothelial Cell Gene Expression in Mouse Models of Hypertension
JG McDermott, BL Goodlett, HA Creed… - Kidney and Blood …, 2024 - karger.com
Introduction: Hypertension (HTN) is a major cardiovascular disease that can cause and be
worsened by renal damage and inflammation. We previously reported that renal lymphatic …
worsened by renal damage and inflammation. We previously reported that renal lymphatic …
Study the Roles of Apoe and Microglia in Alzheimer's Disease Using a Chimeric Mouse Model
A Rao - 2023 - search.proquest.com
Despite strong evidence supporting the involvement of both apolipoprotein E4 (APOE4) and
microglia in Alzheimer's Disease (AD) pathogenesis, the effects of microglia on neuronal …
microglia in Alzheimer's Disease (AD) pathogenesis, the effects of microglia on neuronal …
Investigating the Roles of APOE and Microglia in Alzheimer's Disease Using a Chimeric Mouse Model
AT Rao - 2023 - escholarship.org
Despite strong evidence that apolipoprotein E4 (APOE4) increases Alzheimer's Disease
(AD) risk, the etiology and relevant cell types behind human-specific APOE4-related AD …
(AD) risk, the etiology and relevant cell types behind human-specific APOE4-related AD …
[HTML][HTML] C5aR1 antagonism suppresses inflammatory glial gene expression and alters cellular signaling in an aggressive Alzheimer's model
ND Schartz, HY Liang, K Carvalho, SH Chu… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Alzheimer's disease (AD) is the leading cause of dementia in older adults, and the need for
effective, sustainable therapeutic targets is imperative. Pharmacologic inhibition of C5aR1 …
effective, sustainable therapeutic targets is imperative. Pharmacologic inhibition of C5aR1 …