Bone fracture followed by delayed or non-union typically requires bone graft intervention.
Autologous bone grafts remain the clinical “gold standard”. Recently, synthetic bone grafts …

In the US alone, approximately 500,000 patients annually undergo surgical procedures to
treat bone fractures, alleviate severe back pain through spinal fusion procedures, or promote …

This article presents preliminary clinical evidence of the beneficial effect of the use of plasma
rich in growth factors of autologous origin. The plasma is obtained from the individual patient …

The development of guided bone regeneration (GBR) has substantially influenced the
possibilities for using implants. The use of bone augmentation procedures has extended the …

Progress in understanding the role of bone morphogenetic proteins (BMPs) in craniofacial
and tooth development, the demonstration of stem cells in dental pulp and accumulating …

Background: Conventional dentoalveolar osseous reconstruction often involves the use of
grafting materials with or without barrier membranes. The purpose of this study was to …

A literature review was performed to survey the available information on the potential of
bone growth factors in skeletal reconstruction in the maxillofacial area. The aim of this …

Recently, the first clinical reports on bone regeneration by two recombinant human bone
morphogenetic proteins (rhBMPs), BMP-2 and BMP-7 (also named osteogenic protein-1, OP …

PURPOSE: This phase II study was designed to evaluate 2 concentrations of recombinant
human bone morphogenetic protein-2 (rhBMP-2) for safety and efficacy in inducing …

Polypeptide growth factors (GFs) have been shown to modulate the wound healing
response in both hard and soft tissues. During the past decade, many investigators have …