Value of urine peptides in assessing kidney and cardiovascular disease

A Latosinska, J Siwy, S Faguer, J Beige… - PROTEOMICS …, 2021 - Wiley Online Library
Urinary peptides gained significant attention as potential biomarkers especially in the
context of kidney and cardiovascular disease. In this manuscript the recent literature since …

[HTML][HTML] The role of urinary peptidomics in kidney disease research

J Klein, JL Bascands, H Mischak, JP Schanstra - Kidney international, 2016 - Elsevier
Urinary peptidomics focuses on endogenous urinary peptide content. Many studies now
show the usefulness of this approach for the discovery and validation of biomarkers in …

Noninvasive diagnosis of chronic kidney diseases using urinary proteome analysis

J Siwy, P Zürbig, A Argiles, J Beige… - Nephrology Dialysis …, 2017 - academic.oup.com
Background In spite of its invasive nature and risks, kidney biopsy is currently required for
precise diagnosis of many chronic kidney diseases (CKDs). Here, we explored the …

Association of kidney fibrosis with urinary peptides: a path towards non-invasive liquid biopsies?

P Magalhães, M Pejchinovski, K Markoska… - Scientific Reports, 2017 - nature.com
Chronic kidney disease (CKD) is a prevalent cause of morbidity and mortality worldwide. A
hallmark of CKD progression is renal fibrosis characterized by excessive accumulation of …

Urinary peptide-based classifier CKD273: towards clinical application in chronic kidney disease

C Pontillo, H Mischak - Clinical kidney journal, 2017 - academic.oup.com
Capillary electrophoresis coupled with mass spectrometry (CE-MS) has been used as a
platform for discovery and validation of urinary peptides associated with chronic kidney …

Urinary peptidomic biomarkers in kidney diseases

V Sirolli, L Pieroni, L Di Liberato, A Urbani… - International journal of …, 2019 - mdpi.com
In order to effectively develop personalized medicine for kidney diseases we urgently need
to develop highly accurate biomarkers for use in the clinic, since current biomarkers of …

[HTML][HTML] Larger nephron size, low nephron number, and nephrosclerosis on biopsy as predictors of kidney function after donating a kidney

N Issa, LE Vaughan, A Denic, WK Kremers… - American Journal of …, 2019 - Elsevier
It is unclear whether structural findings in the kidneys of living kidney donors predict
postdonation kidney function. We studied living kidney donors who had a kidney biopsy …

Direct mass spectrometry differentiation of ectopic and eutopic endometrium in patients with endometriosis

LV Adamyan, N Starodubtseva, A Borisova… - Journal of minimally …, 2018 - Elsevier
Abstract Study Objective To introduce a method for the rapid assessment of endometriotic
tissues using direct mass spectrometry (MS)-based lipidomics. Design A prospective …

Diagnostic work-up and specific causes of acute kidney injury

M Darmon, M Ostermann, J Cerda… - Intensive care …, 2017 - Springer
Acute kidney injury (AKI) is common in critically ill patients and associated with grim short-
and long-term outcome. Although in the vast majority of cases AKI is multifactorial, with …

OMICS in chronic kidney disease: focus on prognosis and prediction

M Provenzano, R Serra, C Garofalo, A Michael… - International Journal of …, 2021 - mdpi.com
Chronic kidney disease (CKD) patients are characterized by a high residual risk for
cardiovascular (CV) events and CKD progression. This has prompted the implementation of …