[HTML][HTML] Nanoparticles for cancer therapy: current progress and challenges

S Gavas, S Quazi, TM Karpiński - Nanoscale research letters, 2021 - Springer
Cancer is one of the leading causes of death and morbidity with a complex pathophysiology.
Traditional cancer therapies include chemotherapy, radiation therapy, targeted therapy, and …

Chemistries of bifunctional PROTAC degraders

C Cao, M He, L Wang, Y He, Y Rao - Chemical Society Reviews, 2022 - pubs.rsc.org
Proteolysis targeting chimeras (PROTACs) technology is a novel and promising therapeutic
strategy using small molecules to induce ubiquitin-dependent degradation of proteins. It has …

[HTML][HTML] Nanoparticle-based drug delivery in cancer therapy and its role in overcoming drug resistance

Y Yao, Y Zhou, L Liu, Y Xu, Q Chen, Y Wang… - Frontiers in molecular …, 2020 - frontiersin.org
Nanotechnology has been extensively studied and exploited for cancer treatment as
nanoparticles can play a significant role as a drug delivery system. Compared to …

[HTML][HTML] PROTACs: great opportunities for academia and industry (an update from 2020 to 2021)

M He, C Cao, Z Ni, Y Liu, P Song, S Hao, Y He… - … and Targeted Therapy, 2022 - nature.com
Abstract PROteolysis TArgeting Chimeras (PROTACs) technology is a new protein-
degradation strategy that has emerged in recent years. It uses bifunctional small molecules …

[HTML][HTML] A comprehensive review on the synthesis, characterization, and biomedical application of platinum nanoparticles

M Jeyaraj, S Gurunathan, M Qasim, MH Kang, JH Kim - Nanomaterials, 2019 - mdpi.com
Platinum nanoparticles (PtNPs) are noteworthy scientific tools that are being explored in
various biotechnological, nanomedicinal, and pharmacological fields. They are unique …

Lipid-based drug delivery systems in cancer therapy: what is available and what is yet to come

P Yingchoncharoen, DS Kalinowski… - Pharmacological …, 2016 - ASPET
Cancer is a leading cause of death in many countries around the world. However, the
efficacy of current standard treatments for a variety of cancers is suboptimal. First, most …

The delivery of therapeutic oligonucleotides

RL Juliano - Nucleic acids research, 2016 - academic.oup.com
The oligonucleotide therapeutics field has seen remarkable progress over the last few years
with the approval of the first antisense drug and with promising developments in late stage …

[HTML][HTML] Sol–gel based materials for biomedical applications

GJ Owens, RK Singh, F Foroutan, M Alqaysi… - Progress in materials …, 2016 - Elsevier
Sol–gel chemistry offers a flexible approach to obtaining a diverse range of materials. It
allows differing chemistries to be achieved as well as offering the ability to produce a wide …

Size-controlled synthesis of porphyrinic metal–organic framework and functionalization for targeted photodynamic therapy

J Park, Q Jiang, D Feng, L Mao… - Journal of the American …, 2016 - ACS Publications
The understanding of nanomaterials for targeted cancer therapy is of great importance as
physical parameters of nanomaterials have been shown to be strong determinants that can …

[HTML][HTML] Targeting folate receptor alpha for cancer treatment

A Cheung, HJ Bax, DH Josephs, KM Ilieva… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Promising targeted treatments and immunotherapy strategies in oncology and
advancements in our understanding of molecular pathways that underpin cancer …