The use of multi drug regimens among the elderly population has increased tremendously
over the last decade although the benefits of medications are always accompanied by …

Background: The management of severe Alzheimer disease often presents difficult choices
for clinicians and families. The disease is characterized by a need for full-time care and …

In recent years, the use of antipsychotics has been widely debated for reasons concerning
their safety in elderly patients affected with dementia. To update the use of antipsychotics in …

Objective The authors sought to determine the effects of conventional and atypical
antipsychotic use on time to nursing home admission and time to death in a group of …

This is a study of the metabolic and distal cardiovascular/cerebrovascular outcomes
associated with the use of second‐generation antipsychotics (SGAs) compared to …

Behavioral and psychological symptoms of dementia (BPSD), ie verbal and physical
aggression, agitation, psychotic symptoms (hallucinations and delusions), sleep …

Background and Purpose—Previous studies have identified an array of morbidities following
traumatic brain injury (TBI), including certain neurological disorders. However, no direct …

Based on evidence of an increased risk of death, drug agencies issued safety warnings
about the use of second generation antipsychotics (SGAs) in the elderly with dementia. The …

In this 10-week, double-blind, fixed-dose study, elderly institutionalized patients with
dementia and agitation were randomized (3: 3: 2) to quetiapine 200mg/day, 100mg/day, or …

Dual orthosteric agonists of metabotropic glutamate 2 (mGlu2) and mGlu3 receptors are
being developed as novel antipsychotic agents devoid of the adverse effects of conventional …