[HTML][HTML] The use of iron oxide nanoparticles to reprogram macrophage responses and the immunological tumor microenvironment

V Mulens-Arias, JM Rojas, DF Barber - Frontiers in immunology, 2021 - frontiersin.org
The synthesis and functionalization of iron oxide nanoparticles (IONPs) is versatile, which
has enhanced the interest in studying them as theranostic agents over recent years. As …

Molecular mechanisms of sex hormones in the development and progression of Alzheimer's disease

S Radaghdam, V Karamad, A Nourazarian… - Neuroscience …, 2021 - Elsevier
Alzheimer's disease (AD) is a form of brain disorder characterized by various pathological
changes in the brain. Numerous studies have shown that sex hormones are involved in the …

[HTML][HTML] Melatonin Prevents Depression but Not Anxiety-like Behavior Produced by the Chemotherapeutic Agent Temozolomide: Implication of Doublecortin Cells and …

EA Cabrera-Muñoz, GB Ramírez-Rodríguez… - International Journal of …, 2023 - mdpi.com
Melatonin is a hormone synthesized by the pineal gland with neuroprotective and
neurodevelopmental effects. Also, melatonin acts as an antidepressant by modulating the …

Hijacking Sexual Immuno-Privilege in GBM—An Immuno-Evasion Strategy

MA Sharpe, DS Baskin, AV Jenson… - International Journal of …, 2021 - mdpi.com
Regulatory T-cells (Tregs) are immunosuppressive T-cells, which arrest immune responses
to 'Self'tissues. Some immunosuppressive Tregs that recognize seminal epitopes suppress …

[PDF][PDF] 3D image analysis of the complete ventricular-subventricular zone stem cell niche reveals significant vasculature changes and progenitor deficits in males …

X Zhao, Y Wang, E Wait, W Mankowski, CS Bjornsson… - Stem Cell Reports, 2021 - cell.com
With age, neural stem cell (NSC) function in the adult ventricular-subventricular zone (V-
SVZ) declines, reducing memory and cognitive function in males; however, the impact on …

Neurosteroids: A potential target for neuropsychiatric disorders

M Wang, S Hu, X Fu, H Zhou, S Yang… - The Journal of Steroid …, 2024 - Elsevier
Neurosteroids are steroids produced by endocrine glands and subsequently entering the
brain, and also include steroids synthesis in the brain. It has been widely known that …

Activation of testosterone‐androgen receptor mediates cerebrovascular protection by photobiomodulation treatment in photothrombosis‐induced stroke rats

Y Feng, Z Huang, X Ma, X Zong… - CNS Neuroscience …, 2024 - Wiley Online Library
Rationale Numerous epidemiological studies have reported a link between low testosterone
levels and an increased risk of cerebrovascular disease in men. However, there is ongoing …

[HTML][HTML] The Brain Pre-Metastatic Niche: Biological and Technical Advancements

M Geissler, W Jia, EN Kiraz, I Kulacz, X Liu… - International Journal of …, 2023 - mdpi.com
Metastasis, particularly brain metastasis, continues to puzzle researchers to this day, and
exploring its molecular basis promises to break ground in developing new strategies for …

[HTML][HTML] The Multienzyme Complex Nature of Dehydroepiandrosterone Sulfate Biosynthesis

A Tumilovich, E Yablokov, Y Mezentsev… - International Journal of …, 2024 - mdpi.com
Dehydroepiandrosterone (DHEA), a precursor of steroid sex hormones, is synthesized by
steroid 17-alpha-hydroxylase/17, 20-lyase (CYP17A1) with the participation of microsomal …

[HTML][HTML] Oogenesis in Women: From Molecular Regulatory Pathways and Maternal Age to Stem Cells

K Krajnik, K Mietkiewska, A Skowronska… - International Journal of …, 2023 - mdpi.com
It is a well-known fact that the reproductive organs in women, especially oocytes, are
exposed to numerous regulatory pathways and environmental stimuli. The maternal age is …