Long non-coding RNA in the pathogenesis of cancers

Y Chi, D Wang, J Wang, W Yu, J Yang - Cells, 2019 - mdpi.com
The incidence and mortality rate of cancer has been quickly increasing in the past decades.
At present, cancer has become the leading cause of death worldwide. Most of the cancers …

Long non-coding RNAs in cancer: implications for diagnosis, prognosis, and therapy

Y Qian, L Shi, Z Luo - Frontiers in medicine, 2020 - frontiersin.org
Long non-coding RNAs (lncRNAs) are major components of cellular transcripts that are
arising as important players in various biological pathways. They have received extensive …

LncRNA NNT-AS1/hsa-miR-485–5p/HSP90 axis in-silico and clinical prospect correlated-to histologic grades-based CRC stratification: A step toward ncRNA …

NM El-Sheikh, AI Abulsoud, A Fawzy, EF Wasfey… - … -Research and Practice, 2023 - Elsevier
The oncogenic effects of long non-coding RNA (lncRNA) Nicotinamide Nucleotide
Transhydrogenase-antisense RNA1 (NNT-AS1) role in colorectal cancer (CRC) hasn't been …

Long non-coding RNAs (lncRNAs); roles in tumorigenesis and potentials as biomarkers in cancer diagnosis

S Najafi, SH Khatami, M Khorsand, Z Jamali… - Experimental cell …, 2022 - Elsevier
New research has indicated that long non-coding RNAs (lncRNAs) play critical roles in a
broad range of biological processes, including the pathogenesis of many complex human …

Role of lncRNAs in hepatocellular carcinoma

S Verma, BD Sahu, MN Mugale - Life Sciences, 2023 - Elsevier
Hepatocellular carcinoma (HCC) is among the deadliest cancer in human malignancies. It is
the most common and severe type of primary liver cancer. However, the molecular …

RNA-binding proteins as important regulators of long non-coding RNAs in cancer

K Jonas, GA Calin, M Pichler - International journal of molecular sciences, 2020 - mdpi.com
The majority of the genome is transcribed into pieces of non-(protein) coding RNA, among
which long non-coding RNAs (lncRNAs) constitute a large group of particularly versatile …

Long noncoding RNA ZFPM2-AS1 acts as a miRNA sponge and promotes cell invasion through regulation of miR-139/GDF10 in hepatocellular carcinoma

H He, Y Wang, P Ye, D Yi, Y Cheng, H Tang… - Journal of Experimental …, 2020 - Springer
Background Emerging evidence has shown that dysregulated expression of long noncoding
RNAs (lncRNAs) is implicated in liver hepatocellular carcinoma (HCC). However, the role …

Nuclear-encoded lncRNA MALAT1 epigenetically controls metabolic reprogramming in HCC cells through the mitophagy pathway

Y Zhao, L Zhou, H Li, T Sun, X Wen, X Li… - … Therapy-Nucleic Acids, 2021 - cell.com
Mitochondrial dysfunction is a metabolic hallmark of cancer cells. In search of molecular
factors involved in this dysregulation in hepatocellular carcinoma (HCC), we found that the …

Identification of m6A-and ferroptosis-related lncRNA signature for predicting immune efficacy in hepatocellular carcinoma

H Xie, M Shi, Y Liu, C Cheng, L Song, Z Ding… - Frontiers in …, 2022 - frontiersin.org
Background N6-methyladenosine (m6A) methylation and ferroptosis assist long noncoding
RNAs (lncRNAs) in promoting immune escape in hepatocellular carcinoma (HCC) …

Development and validation of cuproptosis-related gene signature in the prognostic prediction of liver cancer

Y Liu, Y Liu, S Ye, H Feng, L Ma - Frontiers in oncology, 2022 - frontiersin.org
Liver cancer is a generic term referring to several cancer types arising from the liver. Every
year, liver cancer causes lots of deaths and other burdens to the people all over the world …