Proteomics: a groundbreaking development in cancer biology

MA Mir, H Qayoom, S Sofi, N Jan - Proteomics, 2023 - Elsevier
Proteins are the basic unit of any living organism. Proteins are comprised of a variety of
amino acids that drive the structure, stability, and function of proteins. Proteins are the …

Novel Metabolic Signatures of Prostate Cancer Revealed by 1H-NMR Metabolomics of Urine

B Yang, C Zhang, S Cheng, G Li, J Griebel, J Neuhaus - Diagnostics, 2021 - mdpi.com
Prostate cancer (PC) is one of the most common male cancers worldwide. Until now, there is
no consensus about using urinary metabolomic profiling as novel biomarkers to identify PC …

An enhanced hyper-parameter optimization of a convolutional neural network model for leukemia cancer diagnosis in a smart healthcare system

JB Awotunde, AL Imoize, OB Ayoade, MK Abiodun… - Sensors, 2022 - mdpi.com
Healthcare systems in recent times have witnessed timely diagnoses with a high level of
accuracy. Internet of Medical Things (IoMT)-enabled deep learning (DL) models have been …

Integrative metabolomic and transcriptomic analysis for the study of bladder cancer

A Loras, C Suárez-Cabrera, MC Martínez-Bisbal… - Cancers, 2019 - mdpi.com
Metabolism reprogramming is considered a hallmark of cancer. The study of bladder cancer
(BC) metabolism could be the key to developing new strategies for diagnosis and therapy …

An overview of metabolic phenotyping and its role in systems biology

E Holmes, ID Wilson, JC Lindon - The Handbook of Metabolic Phenotyping, 2019 - Elsevier
Understanding the functional relationships between genetic and gene expression variation
and real-world biochemical and physiological end points in human, animal, or plant …

NMR-based metabolomic profiling of urine: Evaluation for application in prostate cancer detection

N MacKinnon, W Ge, P Han, J Siddiqui… - Natural Product …, 2019 - journals.sagepub.com
Detection of prostate cancer (PCa) and distinguishing indolent versus aggressive forms of
the disease is a critical clinical challenge. The current clinical test is circulating prostate …

1H-NMR Based Metabolomics Technology Identifies Potential Serum Biomarkers of Colorectal Cancer Lung Metastasis in a Mouse Model

J Zhang, Y Du, Y Zhang, Y Xu, Y Fan… - Cancer Management and …, 2022 - Taylor & Francis
Background Lung metastasis is a common metastasis site of colorectal cancer which largely
reduces the quality of life and survival rates of patients. The discovery of potential novel …

New bladder cancer non-invasive surveillance method based on voltammetric electronic tongue measurement of urine

J Monreal-Trigo, M Alcañiz, MC Martínez-Bisbal… - Iscience, 2022 - cell.com
Bladder cancer (BC) is the sixth leading cause of death by cancer. Depending on the
invasiveness of tumors, patients with BC will undergo surgery and surveillance lifelong …

GRB2‑associated binding protein 2 regulates multiple pathways associated with the development of prostate cancer

XR Qiao, X Zhang, L Mu, J Tian… - Oncology letters, 2020 - spandidos-publications.com
The development of prostate cancer is complicated and involves a number of tumor‑
associated gene expression level abnormalities. Gene chip technology is a high‑throughput …

Ex Vivo High-Resolution Magic Angle Spinning (HRMAS) 1H NMR Spectroscopy for Early Prostate Cancer Detection

A Steiner, SA Schmidt, CS Fellmann, J Nowak, CL Wu… - Cancers, 2022 - mdpi.com
Simple Summary Prostate cancer is the second leading cancer diagnosed in men
worldwide. Current diagnostic standards lack sufficient reliability in detecting and …