MicroRNAs as therapeutic targets in cardiovascular disease
B Laggerbauer, S Engelhardt - The Journal of clinical …, 2022 - Am Soc Clin Investig
The discovery of microRNAs and their role in diseases was a breakthrough that inspired
research into microRNAs as drug targets. Cardiovascular diseases are an area in which …
research into microRNAs as drug targets. Cardiovascular diseases are an area in which …
Fibrosis in chronic kidney disease: pathogenesis and consequences
S Panizo, L Martínez-Arias, C Alonso-Montes… - International journal of …, 2021 - mdpi.com
Fibrosis is a process characterized by an excessive accumulation of the extracellular matrix
as a response to different types of tissue injuries, which leads to organ dysfunction. The …
as a response to different types of tissue injuries, which leads to organ dysfunction. The …
The roles of microRNAs in the cardiovascular system
F Nappi, SS Avtaar Singh, V Jitendra, A Alzamil… - International Journal of …, 2023 - mdpi.com
The discovery of miRNAs and their role in disease represent a significant breakthrough that
has stimulated and propelled research on miRNAs as targets for diagnosis and therapy …
has stimulated and propelled research on miRNAs as targets for diagnosis and therapy …
Circulating miRNAs as potential biomarkers associated with cardiac remodeling and fibrosis in chagas disease cardiomyopathy
Chagas disease (CD) affects approximately 6–7 million people worldwide, from which 30%
develop chronic Chagas cardiomyopathy (CCC), usually after being asymptomatic for years …
develop chronic Chagas cardiomyopathy (CCC), usually after being asymptomatic for years …
eNAMPT is a novel damage-associated molecular pattern protein that contributes to the severity of radiation-induced lung fibrosis
AN Garcia, NG Casanova, CL Kempf… - American Journal of …, 2022 - atsjournals.org
The paucity of therapeutic strategies to reduce the severity of radiation-induced lung fibrosis
(RILF), a life-threatening complication of intended or accidental ionizing radiation exposure …
(RILF), a life-threatening complication of intended or accidental ionizing radiation exposure …
MicroRNAs—The Heart of Post-Myocardial Infarction Remodeling
Myocardial infarction (MI) is one of the most frequent cardiac emergencies, with significant
potential for mortality. One of the major challenges of the post-MI healing response is that …
potential for mortality. One of the major challenges of the post-MI healing response is that …
[HTML][HTML] Comparison of different chemically modified inhibitors of miR-199b in vivo
B Duygu, R Juni, L Ottaviani, N Bitsch, JBM Wit… - Biochemical …, 2019 - Elsevier
MicroRNAs (miRNAs) have recently received great attention for their regulatory roles in
diverse cellular processes and for their contribution to several human pathologies …
diverse cellular processes and for their contribution to several human pathologies …
miR‐199b‐5p promoted chondrogenic differentiation of C3H10T1/2 cells by regulating JAG1
M Zhang, SZ Yuan, H Sun, L Sun… - Journal of tissue …, 2020 - Wiley Online Library
Mesenchymal stem cells (MSCs) are considered a promising candidate for use in cell‐
based therapy for cartilage repair. To promote understanding of the molecular control of …
based therapy for cartilage repair. To promote understanding of the molecular control of …
Adding a “notch” to cardiovascular disease therapeutics: a MicroRNA-based approach
L Marracino, F Fortini, E Bouhamida… - Frontiers in cell and …, 2021 - frontiersin.org
Dysregulation of the Notch pathway is implicated in the pathophysiology of cardiovascular
diseases (CVDs), but, as of today, therapies based on the re-establishing the physiological …
diseases (CVDs), but, as of today, therapies based on the re-establishing the physiological …
Antagonism of miR-429 ameliorates anoxia/reoxygenation injury in cardiomyocytes by enhancing MO25/LKB1/AMPK mediated autophagy
Q Zhu, F Hu - Life sciences, 2019 - Elsevier
MicroRNAs plays important role in the development of myocardial infarction (MI). The aim of
this study was to analyze whether miR-429 has effect on the process of autophagy in …
this study was to analyze whether miR-429 has effect on the process of autophagy in …