[HTML][HTML] Astrocyte crosstalk in CNS inflammation
M Linnerbauer, MA Wheeler, FJ Quintana - Neuron, 2020 - cell.com
Astrocytes control multiple processes in the nervous system in health and disease. It is now
clear that specific astrocyte subsets or activation states are associated with specific genomic …
clear that specific astrocyte subsets or activation states are associated with specific genomic …
Defining the role of anti-and pro-inflammatory outcomes of interleukin-6 in mental health
M García-Juárez, A Camacho-Morales - Neuroscience, 2022 - Elsevier
Abstract Interleukin-6 (IL-6) is a major cytokine that promotes anti-and pro-inflammatory
outcomes by activating the membrane IL-6 receptor (IL-6R) or the soluble IL-6 receptor (sIL …
outcomes by activating the membrane IL-6 receptor (IL-6R) or the soluble IL-6 receptor (sIL …
[HTML][HTML] Spatiotemporal dynamics of the cellular components involved in glial scar formation following spinal cord injury
C Zhang, J Kang, X Zhang, Y Zhang, N Huang… - Biomedicine & …, 2022 - Elsevier
Spinal cord injury (SCI) triggers complex inflammatory and pathological processes that
ultimately lead to scar formation, thus resulting in the severe and irreversible loss of function …
ultimately lead to scar formation, thus resulting in the severe and irreversible loss of function …
[HTML][HTML] Dynamic responses of microglia in animal models of multiple sclerosis
MJ Plastini, HL Desu, R Brambilla - Frontiers in cellular neuroscience, 2020 - frontiersin.org
Microglia play an essential role in maintaining central nervous system (CNS) homeostasis,
as well as responding to injury and disease. Most neurological disorders feature microglial …
as well as responding to injury and disease. Most neurological disorders feature microglial …
[HTML][HTML] Extracellular vesicles (exosomes and ectosomes) play key roles in the pathology of brain diseases
J Meldolesi - Molecular biomedicine, 2021 - Springer
Last century, neurons and glial cells were mostly believed to play distinct functions, relevant
for the brain. Progressively, however, it became clear that neurons, astrocytes and microglia …
for the brain. Progressively, however, it became clear that neurons, astrocytes and microglia …
[HTML][HTML] Neuroinflammation in HIV-related neuropathic pain
HJ Lu, YY Fu, QQ Wei, ZJ Zhang - Frontiers in Pharmacology, 2021 - frontiersin.org
In the management of human immunodeficiency virus (HIV) infection around the world,
chronic complications are becoming a new problem along with the prolonged life …
chronic complications are becoming a new problem along with the prolonged life …
[HTML][HTML] Exogenous l-fucose attenuates neuroinflammation induced by lipopolysaccharide
X Xu, T Fukuda, J Takai, S Morii, Y Sun, J Liu… - Journal of Biological …, 2024 - ASBMB
α1, 6-Fucosyltransferase (Fut8) catalyzes the transfer of fucose to the innermost GlcNAc
residue of N-glycan to form core fucosylation. Our previous studies showed that …
residue of N-glycan to form core fucosylation. Our previous studies showed that …
Taurochenodeoxycholic acid reduces astrocytic neuroinflammation and alleviates experimental autoimmune encephalomyelitis in mice
N Xu, Y Bai, X Han, J Yuan, L Wang, Y He, L Yang… - Immunobiology, 2023 - Elsevier
Objective Multiple sclerosis (MS) is an immune regulatory disease that affects the central
nervous system (CNS). The main pathological features include demyelination and …
nervous system (CNS). The main pathological features include demyelination and …
[HTML][HTML] Assessing neuroprotective effects of diroximel fumarate and siponimod via modulation of pacemaker channels in an experimental model of remyelination
L Vinnenberg, N Rychlik, T Oniani, B Williams… - Experimental …, 2024 - Elsevier
Cuprizone (CPZ)-induced alterations in axonal myelination are associated with a period of
neuronal hyperexcitability and increased activity of hyperpolarization-activated and cyclic …
neuronal hyperexcitability and increased activity of hyperpolarization-activated and cyclic …
[HTML][HTML] Effects of axonal demyelination, inflammatory cytokines and divalent cation chelators on thalamic HCN channels and oscillatory bursting
T Oniani, L Vinnenberg, R Chaudhary… - International Journal of …, 2022 - mdpi.com
Multiple sclerosis (MS) is a demyelinating disease of the central nervous system that is
characterized by the progressive loss of oligodendrocytes and myelin and is associated with …
characterized by the progressive loss of oligodendrocytes and myelin and is associated with …