Astrocytes control multiple processes in the nervous system in health and disease. It is now
clear that specific astrocyte subsets or activation states are associated with specific genomic …

Abstract Interleukin-6 (IL-6) is a major cytokine that promotes anti-and pro-inflammatory
outcomes by activating the membrane IL-6 receptor (IL-6R) or the soluble IL-6 receptor (sIL …

Spinal cord injury (SCI) triggers complex inflammatory and pathological processes that
ultimately lead to scar formation, thus resulting in the severe and irreversible loss of function …

Microglia play an essential role in maintaining central nervous system (CNS) homeostasis,
as well as responding to injury and disease. Most neurological disorders feature microglial …

Last century, neurons and glial cells were mostly believed to play distinct functions, relevant
for the brain. Progressively, however, it became clear that neurons, astrocytes and microglia …

In the management of human immunodeficiency virus (HIV) infection around the world,
chronic complications are becoming a new problem along with the prolonged life …

α1, 6-Fucosyltransferase (Fut8) catalyzes the transfer of fucose to the innermost GlcNAc
residue of N-glycan to form core fucosylation. Our previous studies showed that …

Objective Multiple sclerosis (MS) is an immune regulatory disease that affects the central
nervous system (CNS). The main pathological features include demyelination and …

Cuprizone (CPZ)-induced alterations in axonal myelination are associated with a period of
neuronal hyperexcitability and increased activity of hyperpolarization-activated and cyclic …

Multiple sclerosis (MS) is a demyelinating disease of the central nervous system that is
characterized by the progressive loss of oligodendrocytes and myelin and is associated with …