Astrocytes are a population of cells with distinctive morphological and functional
characteristics that differ within specific areas of the brain. Postnatally, astrocyte progenitors …

Background: Alzheimer's disease (AD) is a complex neurodegenerative disorder
characterized by the progressive loss of neurons, which typically leads to severe …

Oligodendrocyte precursor cells (OPCs) account for 5% of the resident parenchymal central
nervous system glial cells. OPCs are not only a back-up for the loss of oligodendrocytes that …

Neurodegenerative diseases represent some of the most devastating neurological
disorders, characterized by progressive loss of the structure and function of neurons. Current …

Alzheimer's disease (AD) is a neurodegenerative disorder that usually develops slowly and
progressively worsens over time. Although there has been increasing research interest in …

There is increasing evidence for the involvement of mitochondrial dysfunction and oxidative
stress in the pathogenesis of many of the major neurodegenerative and neuroinflammatory …

Fatty acids (FAs) are typically associated with structural and metabolic roles, as they can be
stored as triglycerides, degraded by β-oxidation or used in phospholipids' synthesis, the …

Peroxisome proliferator-activated receptor gamma coactivator-1 (PGC-1) family (PGC-1s),
consisting of three members encompassing PGC-1α, PGC-1β, and PGC-1-related …

Nuclear receptors, also known as ligand-activated transcription factors, regulate gene
expression upon ligand signals and present as attractive therapeutic targets especially in …

Background Discoveries that microglia-mediated neuroinflammation is involved in the
pathological process of depression provided a new strategy for novel antidepressant …