The Role of Hypoxia and Cancer Stem Cells in Renal Cell Carcinoma Pathogenesis
A Myszczyszyn, AM Czarnecka, D Matak… - Stem cell reviews and …, 2015 - Springer
The cancer stem cell (CSC) model has recently been approached also in renal cell
carcinoma (RCC). A few populations of putative renal tumor-initiating cells (TICs) were …
carcinoma (RCC). A few populations of putative renal tumor-initiating cells (TICs) were …
Targeting strategies for renal cell carcinoma: from renal cancer cells to renal cancer stem cells
Z Yuan, J Mo, G Zhao, G Shu, H Fu… - Frontiers in …, 2016 - frontiersin.org
Renal cell carcinoma (RCC) is a common form of urologic tumor that originates from the
highly heterogeneous epithelium of renal tubules. Over the last decade, targeting therapies …
highly heterogeneous epithelium of renal tubules. Over the last decade, targeting therapies …
Aldehyde dehydrogenase 1 identifies cells with cancer stem cell-like properties in a human renal cell carcinoma cell line
K Ueda, S Ogasawara, J Akiba, M Nakayama… - PloS one, 2013 - journals.plos.org
Cancer stem cells (CSC) or cancer stem cell-like cells (CSC-LCs) have been identified in
many malignant tumors. CSCs are proposed to be related with drug resistance, tumor …
many malignant tumors. CSCs are proposed to be related with drug resistance, tumor …
Tumor-specific isoform switch of the fibroblast growth factor receptor 2 underlies the mesenchymal and malignant phenotypes of clear cell renal cell carcinomas
Purpose: We aim to identify tumor-specific alternative splicing events having potential
applications in the early detection, diagnosis, prognosis, and therapy for cancers …
applications in the early detection, diagnosis, prognosis, and therapy for cancers …
Natural products targeting cancer stem cells: Implications for cancer chemoprevention and therapeutics
K Gairola, S Gururani, A Bahuguna… - Journal of Food …, 2021 - Wiley Online Library
Cancer, being the leading cause of death in the globe, has been one of the major thrust
areas of research worldwide. In a new paradigm about neoplastic transformations, the …
areas of research worldwide. In a new paradigm about neoplastic transformations, the …
Stem cells and extracellular vesicles: biological regulators of physiology and disease
T Borgovan, L Crawford, C Nwizu… - American Journal of …, 2019 - journals.physiology.org
Many different subpopulations of subcellular extracellular vesicles (EVs) have been
described. EVs are released from all cell types and have been shown to regulate normal …
described. EVs are released from all cell types and have been shown to regulate normal …
IL‐8 and CXCR1 expression is associated with cancer stem cell‐like properties of clear cell renal cancer
C Corrò, ME Healy, S Engler… - The Journal of …, 2019 - Wiley Online Library
Recent studies suggest that clear cell renal cell carcinoma (ccRCC) possesses a rare
population of cancer stem cells (CSCs) that might contribute to tumor heterogeneity …
population of cancer stem cells (CSCs) that might contribute to tumor heterogeneity …
Reduced expression of CXCR4, a novel renal cancer stem cell marker, is associated with high-grade renal cell carcinoma
Abstract Purpose Cancer stem cells (CSCs) represent a population with tumour-initiating,
self-renewal, and differentiation potential. This study aimed to evaluate the expression …
self-renewal, and differentiation potential. This study aimed to evaluate the expression …
Effect of cryopreservation on delineation of immune cell subpopulations in tumor specimens as determined by multiparametric single cell mass cytometry analysis
E Kadić, RJ Moniz, Y Huo, A Chi, I Kariv - BMC immunology, 2017 - Springer
Background Comprehensive understanding of cellular immune subsets involved in
regulation of tumor progression is central to the development of cancer immunotherapies …
regulation of tumor progression is central to the development of cancer immunotherapies …
[HTML][HTML] Ecto-5′-nucleotidase (CD73) is a biomarker for clear cell renal carcinoma stem-like cells
L Song, W Ye, Y Cui, J Lu, Y Zhang, N Ding, W Hu… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Identification of a specific biomarker for cancer stem cells (CSCs) is of potential applications
in the development of effective therapeutic strategies for renal cell carcinoma (RCC). In this …
in the development of effective therapeutic strategies for renal cell carcinoma (RCC). In this …