Nonsense-mediated mRNA decay (NMD), also called mRNA surveillance, is an important
pathway used by all organisms that have been tested to degrade mRNAs that prematurely …

A superparamagnetic iron oxide nanoparticles (SPIONs)/doxorubicin (Dox) co-loaded poly
(lactic-co-glycolic acid)(PLGA)-based nanoparticles targeted with AS1411 aptamer (Apt) …

Nucleolin is a RNA-and protein-binding multifunctional protein. Mainly characterized as a
nucleolar protein, nucleolin is continuously expressed on the surface of different types of …

Background Nucleolin is a major component of the nucleolus, but is also found in other cell
compartments. This protein is involved in various aspects of ribosome biogenesis from …

Non‐coding RNA s play a key role in organizing the nucleus into functional
subcompartments. By combining fluorescence microscopy and RNA deep‐sequencing …

Background G-rich sequences undergo unique structural equilibria to form G-quadruplexes
(G4) both in vitro and in cell systems. Several pathologies emerged to be directly related to …

Recent evidence for efficient delivery of macromolecules, such as peptides and nucleic
acids, from the cell exterior to the nucleus offers the interesting possibility of developing …

The structure of the 28 kDa complex of the first two RNA binding domains (RBDs) of
nucleolin (RBD12) with an RNA stem–loop that includes the nucleolin recognition element …

The intrinsically disordered RG/RGG repeat domain is found in several nucleolar and P-
granule proteins, but how it influences their phase separation into biomolecular …

The discovery of G-rich oligonucleotides (GROs) that have non-antisense antiproliferative
activity against a number of cancer cell lines has been recently described. This biological …